Internuclear Ophthalmoplegia, Multiple Sclerosis
Conditions
Brief summary
Internuclear ophthalmoplegia is a symptom frequently associated with multiple sclerosis (MS), although other etiologies are possible. Some patients do not meet the diagnostic criteria for MS at the time of the internuclear ophthalmoplegia episode but subsequently convert to MS. Studying this specific clinical situation may help enable earlier diagnosis of MS. The objective is to analyze the proportion of patients with isolated internuclear ophthalmoplegia who convert to multiple sclerosis and to identify factors associated with this conversion. The study hypothesis is that the presence of internuclear ophthalmoplegia is highly suggestive of multiple sclerosis, particularly when cerebrospinal fluid-specific oligoclonal bands are present.
Interventions
None listed
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with internuclear ophthalmoplegia listed as a primary or associated diagnosis * Patients hospitalized in a neurology department
Exclusion criteria
\- Patients under 18 years of age
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Analyze the proportion of patients with isolated internuclear ophthalmoplegia who convert to multiple sclerosis. | 1 year | Proportion of patients with isolated internuclear ophthalmoplegia who converted to multiple sclerosis during follow-up. |
Countries
France
Contacts
CONTACTKévin BIGAUT
CONTACTSebille COLIN
PRINCIPAL_INVESTIGATORKévin BIGAUT
Hôpitaux Universitaires de Strasbourg
Outcome results
None listed