Colorectal Cancer
Conditions
Brief summary
This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to look at colorectal cancer (CRC) patients younger than 35 and comparing them against CRC patients older than 35 years of age.
Detailed description
Specifically, investigator want to investigate the effect of having a diagnosis of CRC before the age of 35 years on:disease stage at presentation, insurance status at diagnosis, treatment patterns by stage, and adjusted cancer-specific survival. The hypothesis is that patients younger than 35 years of age with CRC will present with more advanced disease at diagnosis but will have longer survival overall through more aggressive therapy.
Interventions
OTHERColorectal cancer
CRC is a disease that is often associated with older adults (\<50 years). CRC remains the second most common cause of cancer death in males and the third most common cancer death in women. Despite this, CRC incidence has steadily declined in older adults; however, there is a concerning rise of incidence of colorectal cancer in young patients. The incidence of CRC in men and women under the age of 50 steadily increased 2.1 percent per year from 1992 through 2012.
Sponsors
Methodist Health System
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
35 Years to No maximum
Inclusion criteria
* Colorectal cancer
Exclusion criteria
* No Colorectal cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Age | 20 years | colorectal cancer (CRC) patients younger than 35 years and comparing them against CRC patients older than 35 years of age. |
Countries
United States
Contacts
CONTACTCrystee Cooper, DHEd
CONTACTKavya Mankulangara
PRINCIPAL_INVESTIGATORRohan Jeyarajah, MD
Methodist Health System
Outcome results
None listed