Risk Factors and Predictive Model for Inflammatory Polyps in Ureteral Stones

Risk Factors and Development of a Predictive Model for Stone-Associated Inflammatory Ureteral Polyps: A Retrospective Cohort Study With Prospective Validation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07559721

Acronym

UROLITH-POLYP

Enrollment

779

Registered

2026-04-30

Start date

2018-01-01

Completion date

2027-02-01

Last updated

2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ureteral Calculi

Brief summary

This is a single-center, observational study including a retrospective cohort and a prospective validation cohort. The study aims to identify independent risk factors for inflammatory ureteral polyps in patients with ureteral calculi and develop a preoperative predictive model. The retrospective part will analyze clinical and imaging data of patients treated at the First Hospital of Jilin University between 2018 and 2025. The prospective part is currently recruiting participants to validate the model. The primary outcome is the intraoperative diagnosis of inflammatory ureteral polyps.

Detailed description

This is a bicentric bidirectional cohort study; retrospective cohort (n=629) has been fully enrolled, prospective cohort is ongoing consecutive enrollment.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Inclusion criteria

* Patients aged 18 years or older undergoing ureteroscopic surgery for ureteral calculi at the First Hospital of Jilin University. * Complete clinical and imaging data available.

Exclusion criteria

* Patients with bilateral ureteral calculi. * Patients with preoperative nephrostomy or indwelling ureteral stent. * Patients with a history of ureteral or bladder cancer. * Patients with congenital ureteral anomalies or previous ureteral surgery. * Patients with severe coagulation disorders or contraindications to ureteroscopy. * Patients unable to provide informed consent.

Design outcomes

Primary

Measure	Time frame	Description
Number of Participants with Intraoperatively Confirmed Inflammatory Ureteral Polyps	At the time of ureteroscopic surgery	The primary outcome is the presence or absence of inflammatory ureteral polyps confirmed by intraoperative pathology or direct visualization during ureteroscopy.

Countries

China

Outcome results