Healthy Lifestyle
Conditions
Keywords
power lifting, gym, force, imtp
Brief summary
comparing the effect of hyperoxygenated environment on maximal muscle strength in the Mid-thigh Pull Task
Detailed description
All three major energy systems - phosphagen, glycolytic, and oxidative - contribute to any given physical effort. However, it has been widely deemed that the contribution of the oxidative energy system (aerobic) to motor tasks at the very high end of the intensity spectrum, such as maximal muscle strength efforts, is close to negligible. Hyperoxygenated environment includes the inhalation of 100% oxygen at pressures exceeding one atmosphere absolute (ATA) in order to enhance the amount of oxygen dissolved in the body tissues. During hyperbaric chamber treatment, the arterial O2 tension typically exceeds 1500 mmHg, and levels of 200-400 mmHg occur in different body tissues. The isometric mid-thigh pull test (IMTP) is an increasingly popular means to evaluate muscle strength in a multi-joint, large muscle-mass, mostly lower-body motor task. Our study aims to determine whether a high availability of muscle tissue oxygen, by means of hyperbaric oxygenation, can influence the putative small contribution of the oxidative energy system significantly enough to affect peak-force production in a maximal IMTP.
Interventions
The HYPEROXYGENATED ENVIRONMENT protocol will include a single exposure to hyperoxic environment. The session will last 60 minutes, of 100% oxygen inhalation by mask at 2 ATA
DEVICESham
The Sham protocol will include a single session of breathing 21% oxygen by mask while in the same multi-place chamber. SHAM pressure will go up to 1.2 ATA during the first five minutes of the session (to simulate the pressure sensation in the ears), and then decrease during the next 5 minutes to 1.03 ATA for 55 minutes
Sponsors
Assaf-Harofeh Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
the participants, investigators and outcome assessors will be blinded from the group allocation
Intervention model description
Eligible participants will be randomized to one of the study groups at a 1:1 ratio : Group-1: HYPEROXYGENATED ENVIRONMENT (HOE) first, SHAM second. Group-2: SHAM first, HYPEROXYGENATED ENVIRONMENT (HOE) second.
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
1. Healthy 2. Ages 18-45 3. Participants are physically active and have a recent resistance-training experience of at least six months, ≥ 3 times a week 4. Participant willing and able to read, understand and sign an informed consent
Exclusion criteria
1. Inability to attend scheduled clinic visits or comply with the study protocol 2. Active malignancy 3. Active smokers 4. Previous treatment of hyperbaric chamber for any reason prior to study enrollment. 5. Chest pathology incompatible with pressure changes 6. Major orthopedic injury at the past 3 months 7. Inner ear disease 8. Lung pathology 9. Claustrophobia 10. Previous neurologic conditions (e.g., epilepsy, brain tumors or s/p neurosurgery etc.) 11. Comorbidities and medications that rule out the subject
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximal static muscle force production | Baseline evaluation, IMPT test in HBOT chamber, Approximately 4 weeks after the first visit, participants will be exposed to the opposite intervention - HOE or SHAM - and will undergo the same isometric mid-thigh pull (IMTP) test in the chamber. | Participants will perform the isometric mid-thigh pull (IMTP) test using an analog dynamometer that will be purchased for the purpose of the study |
Countries
Israel
Contacts
CONTACTEldad mr Yaakobi
Outcome results
None listed