Effect of Diode Laser and 20% Benzocaine Anesthetic Gel on Pain Reduction Following Tooth Separation With Elastomeric Separators in Fixed Orthodontic Patients: A Randomized Trial in Karachi-Pakistan

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07558720

Enrollment

Registered

2026-04-30

Start date

2025-12-01

Completion date

2026-04-01

Last updated

2026-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

We Are Not Studying a Disease or Condition, Pain Reduction

Brief summary

The goal of this clinical trial is to learn if low level laser therapy works equivalent to benzocaine in reducing the pain caused by separators in fixed orthodontic treatment. The main questions it aims to answer are: Is there any difference in mean pain scores with Low Level Laser Therapy (LLLT) and 20% Benzocaine anesthetic gel of patients receiving elastomeric separators in fixed orthodontic treatment? Researchers will compare low level laser therapy to benzoaine gel to evaluate reduction in pain Participants will be applied low level laser at the appointment of separator placement and patient himself will apply benzocaine gel thrice daily at the site of separator placement. patient will use placebo on the other side. Gel and placebo would be applied for one month. Patient will take the gel for 7 days.

Interventions

OTHERLaser

Low level laser therapy will be used to reduce pain

OTHERBenzocaine 20%

20% benzocaine gel to be administered by patient himself

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 25 Years

Healthy volunteers

Yes

Inclusion criteria

* \- Patient aged 18-25 years * no history of previous orthodontic treatment * healthy and complete erupted dentition including permanent second molars * good periodontal health( on basis of periodontal index) * Tight proximal contacts of all permanent first molars (both mesially and distally)

Exclusion criteria

* \- Patients with multiple fillings, root canal treatments, gingivitis,, missing teeth, or spacing between molars and premolars will be excluded from the sample * Severely rotated teeth * posterior open bite * any systematic disease

Design outcomes

Primary

Measure	Time frame	Description
mean difference in pain scores	from day of separator placement for 7 days	mean difference in pain scores between the two treatments (LLLT and benzocaine gel)

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 1, 2026