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Clinical Practices of Extubation After Invasive Mechanical Ventilation

Clinical Practices of Extubation After Invasive Mechanical Ventilation in Anesthesia and Intensive Care

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07554586
Acronym
EPP/EPP = 1
Enrollment
200
Registered
2026-04-28
Start date
2026-04-28
Completion date
2026-10-01
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Critical Care, Intensive Care, Extubation, Mechanical Ventilation

Brief summary

Extubation is a delicate and complex phase of airway management in anesthesia and critical care. A variety of complications are of concern, ranging from transient hypoxemia to the need for reintubation, which can then become life-threatening for the patient. For this procedure, it may be recommended to use the positive end-expiratory pressure (PEEP) extubation technique to reduce the risks of hypoxemia, atelectasis, and aspiration. However, no specific technique is preferred given the diversity of described procedures (spontaneous ventilation on an auxiliary circuit, PEEP-assisted spontaneous ventilation, adjustment of the APL valve). However, results may vary depending on the patient population (children, adults) and the setting (operating room, intensive care unit). Given the lack of a preferred technique for performing extubation under positive end-expiratory pressure, the aim of this study is to describe the techniques used by healthcare professionals (physicians, nurse anesthetists, nurses) during the extubation of a surgical or intensive care patient.

Interventions

None listed

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Physicians and students in anesthesiology and critical care, * Critical care physicians, * State-certified nurse anesthetists (IADE), * State-certified nurses (IDE) working in an anesthesia or intensive care team * Students (medical or nurse anesthetist) with at least 1 year of extubation experience.

Exclusion criteria

* Healthcare professionals with no experience in extubation (less than one year of practice) Refusal to participate

Design outcomes

Primary

MeasureTime frameDescription
Extubation techniquebaselineFrequency of use of the simple suction extubation technique compared to the positive-pressure extubation technique (%)

Countries

France

Contacts

CONTACTJean Yves LEFRANT, PHD
jean.yves.lefrant@chu-nimes.fr+33 466 68 30 50
STUDY_DIRECTORAnissa MEGZARI

Centre Hospitalier Universitaire de Nīmes

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 5, 2026