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Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia

Impact of Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07552116
Acronym
intervention
Enrollment
40
Registered
2026-04-27
Start date
2026-04-06
Completion date
2026-05-30
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia

Keywords

Laser, Immune, Pneumonia, Dawn syndrome

Brief summary

Objective: The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, were included into ; group (A) received low intensity laser therapy, inspiratory muscle training in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.

Detailed description

The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.

Interventions

OTHERlow intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements

low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements

OTHERreceived inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

Sponsors

Badr University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Intervention model description

Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.

Eligibility

Sex/Gender
ALL
Age
3 Years to 5 Years
Healthy volunteers
No

Inclusion criteria

* Dawn Syndrome children with pneumonia * Mean age of 3.73±1.82 year * Children were in the first attack of bronchopneumonia.

Exclusion criteria

* Other chest disease

Design outcomes

Primary

MeasureTime frameDescription
IgGat baseline and after one monthImmunoglobulin-G (mg/dl)
IgAat baseline and after one monthImmunoglobulin-A(mg/dl)
IgMat baseline and after one monthImmunoglobulin-M (mg/dl)
WBCsat baseline and after one monthWhite blood cells (thousands/mm3)

Secondary

MeasureTime frameDescription
RRat baseline and after one monthRespiratory Rate(breath/minute)
SaO2at baseline and after one monthArterial oxygen saturation(%)

Countries

Egypt

Contacts

CONTACTMona Mohamed Abdelkhalek, assistance professor
mona.abdelkhalek@buc.edu.eg00201024056108
PRINCIPAL_INVESTIGATORMona Mohamed Abdelkhalek, assistance prof

Badr University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 28, 2026