Androgenetic Alopecia (AGA)
Conditions
Keywords
Androgenetic alopecia, Platelet-rich plasma, Minoxidil, Dermoscpe
Brief summary
A study on the therapeutic effect of platelet-rich plasma in the treatment of androgenetic alopecia
Detailed description
This study included 30 patients with moderate and severe androgenic alopecia and randomly divided into two groups, group A was treated with platelet-rich plasma (once 4 weeks for 3 times) combined with external Minoxidil(5% for male, 2% for female, twice a day, 1 ml each time) , group B was treated with external Minoxidil. The patients in both groups were examined by dermoscopy before the first treatment and 1,2,3 and 6 months after the treatment. The scalp MRI was performed before the first treatment and 6 months after the treatment, the number, density and depth of hair follicles were measured to evaluate the efficacy and safety of platelet-rich plasma combined with Minoxidil in the treatment of androgenic alopecia.
Interventions
DRUGPRP
group A was treated with platelet-rich plasma combined with external Minoxidil , group B was treated with external Minoxidil
Sponsors
The First Affiliated Hospital of Soochow University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* moderate to severe androgenic Alopecia
Exclusion criteria
* abnormal coagulation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dermoscope | before the first treatment and 1,2,3 and 6 months after the treatment | The amount of hair on the parietal and posterior occipital regions |
| MRI | before the first treatment and 6 months after the treatment | Hair follicle density on the parietal and posterior occipital regions |
Countries
China
Outcome results
None listed