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Uterine Position and Pain and Central Sensitization Parameters in Women With Chronic Low Back Pain

The Relationship Between Uterine Position and Pain and Central Sensitization Parameters in Women With Chronic Low Back Pain

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07549009
Enrollment
128
Registered
2026-04-23
Start date
2026-03-16
Completion date
2026-04-16
Last updated
2026-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Back Pain

Brief summary

Female patients aged 18-75 years with chronic low back pain (lasting at least 3 months) will be included in the study. Demographic data including age, height, weight, educational status, marital status, and comorbidities will be recorded. In addition, clinical characteristics such as pain duration, pain distribution, analgesic use, and concomitant musculoskeletal disorders will be assessed. Uterine position will be evaluated based on pelvic magnetic resonance imaging (MRI) or pelvic ultrasonography reports obtained within the last year. According to uterine position, participants will be divided into two groups: posteriorly positioned uterus (retroverted and/or retroflexed uterus) and anteriorly positioned uterus (anteverted uterus). Pain severity will be assessed using the Visual Analog Scale (VAS), and pain duration will be recorded in months. Pressure pain threshold measurements will be performed using an algometer at bilateral lumbar paraspinal muscles, gluteal regions, and the mid-deltoid muscle as a remote control point. Central sensitization will be assessed using the Central Sensitization Inventory (CSI), and pain catastrophizing will be evaluated using the Pain Catastrophizing Scale (PCS). All assessments will be conducted through face-to-face interviews. No additional laboratory tests, interventional procedures, or treatments will be applied to the participants within the scope of the study. Validated Turkish versions of all scales will be used. The collected data will be analyzed to investigate the relationship between uterine position and pressure pain threshold, central sensitization, and pain catastrophizing levels in women with chronic low back pain.

Interventions

OTHERNo intervention

No intervention

Sponsors

Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 75 Years

Inclusion criteria

Female, aged 18-75 years Presence of chronic low back pain (lasting at least 3 months) Availability of pelvic MRI and/or pelvic ultrasonography within the last year with assessable uterine position (anteverted, retroverted, retroflexed) Ability to read and understand Turkish and complete questionnaires Willingness to participate

Exclusion criteria

Pregnancy or childbirth within the last 6 months (postpartum period) History of lumbar spine surgery, vertebral fracture, or spinal malignancy Presence of inflammatory rheumatic disease (e.g., ankylosing spondylitis), severe neurological disease, or systemic disease affecting low back pain Severe cognitive impairment, communication problems, or major psychiatric disorder preventing participation Absence of pelvic imaging or inability to classify uterine position

Design outcomes

Primary

MeasureTime frameDescription
Pressure Pain Threshold (PPT)BaselinePressure pain threshold (kg/cm²) will be measured using an algometer at bilateral lumbar paraspinal muscles, gluteal regions, and the mid-deltoid muscle as a remote control point. Lower values indicate increased pain sensitivity.

Secondary

MeasureTime frameDescription
Visual Analog Scale (VAS)BaselinePain intensity will be assessed using a 10-cm visual analog scale, where higher scores indicate greater pain severity.
Central Sensitization Inventory (CSI)BaselineCSI scores range from 0 to 100, with higher scores indicating greater central sensitization.
Pain Catastrophizing Scale (PCS)BaselineThe PCS assesses catastrophic thinking related to pain. Higher scores indicate greater pain catastrophizing.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 24, 2026