Skin Folds
Conditions
Brief summary
This study investigates the effect of different dressings on skin pH when applied to a simulated skin fold environment.
Detailed description
This study evaluates the impact of various dressings on skin pH when applied to a simulated skin fold environment. To replicate the occlusive conditions commonly found in skin folds, a non-breathable film will be placed over the dressings, maintaining occlusion for approximately 24 hours. Skin pH measurements will be taken during two separate visits: once before dressing application and again after approximately 24 hours of wear time. Both measurements will be conducted on the same location on the forearms of healthy participants. The goal is to investigate how different dressings influence skin pH under occlusive conditions.
Interventions
DEVICEDressings
Sorbact® Ribbon, Sorbact® Compress and InterDry®
Sponsors
Essity Hygiene and Health AB
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
1. Written informed consent to participate in this study 2. Healthy men and women between 18-80 years 3. Patient is mentally and physically able to participate in this study 4. Intact skin on the forearms without any signs of irritation 5. Agreed on not to shower or use cosmetic products on the arms the same day as visit 1 and during the study period 6. Agreed not to engage in intense physical activity throughout the study period
Exclusion criteria
1. Skin disorder of any kind. 2. Known allergy to adhesives or/and any other component(silver) in the investigation devices. 3. Pregnant or lactating women. 4. Presence of tattoos on the forearms. 5. Ongoing medication with antibiotic. 6. Suffer from excessive sweating, hyperhidrosis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference in skin pH | 24 hours of wear time | Difference in skin pH between the simulated skin fold and the area under Sorbact® Compress, measured after approximately 24 hours of wear time |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Difference in skin pH | 24 hour of wear time | Difference in skin pH between the simulated skin fold and the area under Sorbact® Compress, |
| Change in skin hydration under occlusion from baseline | 24 hours of wear time | Change in skin hydration from baseline to after wear time, measured in the simulated skinfold under occlusion using a moisture meter |
Countries
Sweden
Contacts
CONTACTFana Hunegnaw
Outcome results
None listed