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Systemic Immun Inflamation Score Corelation in Postoperative Patients Prognosis

Prognostic Value of Systemic Immun Inflamation Index in Geriatrik Patient Admitted to the ICU After Surgery: A Prospective Observational Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07544719
Enrollment
150
Registered
2026-04-22
Start date
2026-06-15
Completion date
2026-07-30
Last updated
2026-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Geriatric Anesthesia, Postop Adult ICU Patients

Brief summary

The Systemic Immuno-Inflammation Index (SII) is a ratio derived from complete blood count parameters (neutrophils, lymphocytes, platelets) and is a non-invasive and easily calculable biomarker. The SIPI effectively reflects both local and systemic inflammatory responses in the human body. It has been used to predict and evaluate the prognosis of various solid tumors such as gastric cancer, non-small cell lung cancer, and colorectal cancer. Furthermore, the SIPI has been shown to have significant prognostic value in cardiovascular and cerebrovascular diseases. In this study, the SIPI will be calculated using laboratory data at the time of admission to the intensive care unit, and the relationship between the obtained values and the 30-day mortality status of the patients will be analyzed.

Interventions

None listed

Sponsors

Malatya Egitim Ve Arastirma Hastanesi
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* The patient must be 65 years of age or older (in the geriatric age group), * Admitted to the intensive care unit after elective or emergency surgery * Have access to complete blood count (hemogram) data (neutrophils, lymphocytes, platelets) during their stay in the intensive care unit * Be able to undergo 30-day mortality monitoring from the date of admission to the intensive care unit * Have provided informed consent from the patient or their legal representative.

Exclusion criteria

* Patients under 65 years of age * Patients admitted to the intensive care unit for non-surgical reasons (e.g., trauma, medical intensive care indications) * Patients with deficient neutrophil, lymphocyte, or platelet counts upon admission to the intensive care unit * Patients with a history of malignancy, hematological disease, or immunosuppressive therapy * Terminally ill palliative patients * Patients who refuse informed consent.

Design outcomes

Primary

MeasureTime frameDescription
Measuring the Systemic Immune-Inflammation Index (SII) in postoperative patients to see the parameter's predictibility of 30-day mortalityPostoperative day 1In geriatric patients admitted to the intensive care unit after surgery, the Systemic Immune-Inflammation Index (SII) is a significant biomarker for predicting 30-day mortality.

Contacts

CONTACTAyşe Yılkınç Tekirdaş
ylknc.ys.44@hotmail.com+905395721741

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 23, 2026