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Assessment of Risk Factors for Acquiring Colonization With Candida Auris During an Outbreak in ICU.

Assessment of Risk Factors for Acquiring Colonization With Candida Auris During an Outbreak in ICU.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07544342
Enrollment
771
Registered
2026-04-22
Start date
2026-02-15
Completion date
2026-05-01
Last updated
2026-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candida Auris Colonization

Keywords

colonization, ICU, candida auris

Brief summary

The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.

Detailed description

Candida auris is unique when compared to other pathogenic fungi, as it spreads in the hospital rapidly. Therefore, it can cause healthcare-associated infections and outbreaks, it is resistant to antimicrobials and disinfectants and it is persisting on human skin and in the inanimate environment. There are few works listing factors found associated with candida auris candidemia, including longer CVC days, prior antibiotics, mechanical ventilation and longer ICU stay. Most of the research for candida auris risk factor doesn't differentiate colonization and infection, or, focuses on risk factors leading from colonization to infection. The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.

Interventions

None listed

Sponsors

Barzilai Medical Center
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* hospitalization in ICU * Screened for candida auris

Exclusion criteria

* Age \<18 yeas. * No data. * No candida screen.

Design outcomes

Primary

MeasureTime frameDescription
Colonization with Candida aurisFrom hospitalization in ICU until 2 weeks following discharge from ICU, a maximum of 90 days.Positive screening for candida auris, taken by nose/ armpits and groin swabs and either directly seeded on a selective medium or by positive PCR.

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 21, 2026