Common Warts (Verruca Vulgaris)
Conditions
Keywords
PRF injection
Brief summary
this study aims to compare the efficacy and safety of platelet rich fibrin injection versus intralesional vitamin D injection in the treatmentof common warts. PRF, as an autologous biological material , may enhance tissue regeneration and immune response.
Interventions
BIOLOGICALPRF group
intralesional PRF injection in common warts
DRUGVitamin D
intralesional vitamin D injection in common wart
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \- Age more than or equal to 18 years * Clinically and dermoscopically confirmed Common warts of both sex * patient not receiving previous treatment at least one month before recruitment in our study * Single or multiple lesions suitable for injection.
Exclusion criteria
* Chronic Systemic desise (DM , HTN , Autoimmune , immunosuppressive disorders eg , lupus , renal or hepatic failure ) or Hematologic Conditions (anemia : hemoglobin level below 10 g/dl , thrombocytopenia : platelet count below 150,000 /µL ) Infectious Diseases , Local bacterial or fungal infection at the lesions . Pregnancy, Lactation , patients who has hypersensitivity of vitamin D .
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| treatment of common wart by PRF injection ( Mild response: < 50% reduction in lesion size , Moderate response: ≥ 50% reduction in lesion size , to measure the change in lesion size , is the patient satisfied or not ) | 1 session every 2 weeks for 3 months | treatment of common wart by intralesional injection of PRF |
| changes in common warts after treatment by PRF (measuring complete clearance and recurrence of the lesions ,asking about patient satisfaction ) | 6 months after the last session | — |
Countries
Egypt
Contacts
CONTACTbasma alaaeldin mohamed, resident
Outcome results
None listed