Kidney Diseases
Conditions
Brief summary
Renal diseases in children present with a wide spectrum of clinical manifestations, ranging from mild urinary abnormalities to severe acute kidney injury requiring urgent management. Early recognition in the emergency setting is essential to improve outcomes, yet data on pediatric renal emergencies in Upper Egypt remain limited. This prospective cohort study aims to characterize the clinical presentations of renal diseases among children presenting to the emergency room at Sohag University Hospitals, determine the prevalence of specific renal conditions, and evaluate immediate management outcomes and short-term follow-up after discharge.
Interventions
Participants receive routine clinical assessment, investigations, and management according to Sohag University Hospitals emergency protocols. No study-specific intervention is applied.
Sponsors
Study design
Eligibility
Inclusion criteria
* Children aged 1 month to 18 years. Presentation to the emergency room at Sohag University Hospitals with signs and/or symptoms suggestive of renal involvement (e.g., edema, hematuria, oliguria/anuria, flank pain, hypertension). Patients with a known history of renal disease presenting with acute exacerbation. Written informed consent obtained from parents or legal guardians.
Exclusion criteria
* Incomplete or missing essential clinical, laboratory, or imaging data. Refusal or inability to obtain written informed consent from parents or legal guardians. Patients with suspected renal symptoms later confirmed to have non-renal causes. Patients who received renal replacement therapy prior to presentation at another facility.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of Clinical Presentations and Final Diagnoses of Pediatric Renal Diseases | At baseline (emergency room presentation) through hospital stay (up to discharge, typically within 7 days) | Percentage (%) of patients presenting with specific clinical features (e.g., edema, hematuria, oliguria, hypertension) assessed by clinical examination and initial laboratory investigations. Distribution (%) of final diagnoses (e.g., acute kidney injury, urinary tract infection, congenital anomalies, glomerular diseases) based on clinical evaluation, laboratory results, and imaging studies. |