Pain Management, Peripheral Nerve Block, Renal Transplantation
Conditions
Keywords
Renal Transplantation, Transversalis Fascia Plane Block
Brief summary
Renal transplantation is a major surgical procedure associated with significant postoperative pain, particularly due to lower abdominal incision, deep tissue dissection, and extensive surgical manipulation. Effective postoperative pain control is therefore of great importance in this patient population, as inadequate analgesia may impair early mobilization, delay recovery, increase opioid consumption, and contribute to opioid-related adverse effects. In addition, optimal analgesic management may improve patient comfort and support enhanced postoperative outcomes. Nerve blocks reduces opioid consumption in the postoperative period by providing better pain control and therefore has advantages such as fewer side effects and less risk of pulmonary and cardiac complications. In this study; it was aimed to compare the analgesic effectiveness of transversalis fascia plane block in the postoperative period in patients who underwent renal transplantation.
Interventions
This procedure will be performed unilaterally on the surgical side. 30 ml of 0.25% bupivacaine will be injected for ultrasound-guided transversalis fascia plane block application. The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.
PROCEDUREControl Group
No peripheral nerve block will be performed. The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.
Sponsors
Ankara Etlik City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 18-65 years * American Society of Anesthesiologists (ASA) score III * Body Mass Index (BMI) between 18-30 kg/m2
Exclusion criteria
* Patients under 18 and over 65 years of age * Patients with an ASA score other than III * Patients with a history of bleeding diathesis * BMI below 18 or above 30 kg/m2
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain Scores | On the operation day | Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 12th, and 24th hours after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intraoperative opioid consumption | Intraoperative period | Remifentanil consumption for intraoperative period will be recorded |
| Postoperative Opioid Consumption | On the operation day | Opioid consumption for 24 hours will be recorded |
Countries
Turkey (Türkiye)
Contacts
CONTACTAtakan Sezgi
CONTACTJülide Ergil
Outcome results
None listed