Autonomic Nervous System Disease
Conditions
Keywords
Arterial baroreflex, Autonomic nervous system, Skin sympathetic nerve activity, Blood pressure, Resonance intervention
Brief summary
This study aimed to compare the acute autonomic and hemodynamic effects of two arterial baroreflex resonance interventions-Resonance Breathing (RB) and Postural Resonance (PR)-in healthy young adults. Methods: A randomized crossover design was conducted in 27 healthy participants (aged 18-25). Each participant completed three experimental sessions (control, RB, and PR) separated by a 5-day washout period. Each session included a 15-minute baseline, a 15-minute intervention, and a 5-min recovery phase. Continuous recordings of skin sympathetic nerve activity (SKNA) and heart rate variability (HRV) were collected throughout each session, while blood pressure (BP) and pulse wave velocity (PWV) were measured before and after the interventions.
Interventions
BEHAVIORALResonance Breathing
A structured intervention focusing on resonance breathing ( slow, rhythmic breathing at spontaneous resonance frequency ) . The protocol aims to acutely modulate autonomic nervous system activity and hemodynamic responses via stimulation of the arterial baroreflex.
BEHAVIORALPostural Resonance
A structured intervention focusing on postural resonance alignment. The protocol aims to acutely modulate autonomic nervous system activity and hemodynamic responses via stimulation of the arterial baroreflex. Sessions include guided breathing practice, postural adjustment, and feedback on breathing mechanics
Sponsors
Beijing Sport University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* 18-30 years old
Exclusion criteria
* No history of systematic professional sports training; Right-hand dominance (as assessed by the Edinburgh Handedness Inventory). Participants were excluded from the study if they had any of the following: Smoking, chronic alcohol consumption, or the use of psychotropic drugs or other substances affecting the nervous system; Irregular menstrual cycle; History of peripheral neuropathy or other autonomic nervous system disorders; Pre-existing cardiovascular diseases or abnormal electrocardiograms (ECG); Use of hormonal contraceptives; Uncontrolled hypertension or hypotension; Recent major life stressors; Regular practice of meditation or participation in psychotherapy; Presence of any movement disorders or inability to comprehend the experimental instructions.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Skin sympathetic nerve activity | Baseline (pre-intervention) and immediately post-intervention (within 5 minutes of intervention completion) | Skin sympathetic nerve activity (SKNA) was recorded non-invasively at the chest wall using a dedicated SKNA monitoring system. Measurements were obtained at baseline (pre-intervention) and immediately following completion of the resonance breathing and postural resonance intervention, to assess acute changes in sympathetic nervous system activity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Resting Systolic and Diastolic Blood Pressure | Baseline (pre-intervention) and immediately post-intervention (within 5 minutes of intervention completion) | Resting systolic and diastolic blood pressure were measured in a seated position using a validated automated sphygmomanometer. Measurements were collected at baseline (pre-intervention) and immediately post-intervention, to evaluate acute hemodynamic changes following the resonance breathing and postural resonance intervention. |
| Changes in Pulse Wave Velocity (PWV) | Baseline (pre-intervention) and immediately post-intervention (within 5 minutes of intervention completion) | Pulse wave velocity (PWV), a non-invasive marker of arterial stiffness, was assessed using a validated vascular screening device. Measurements were obtained at baseline (pre-intervention) and immediately post-intervention, to evaluate acute changes in arterial function following the intervention. |
Countries
China
Outcome results
None listed