Parkinson Disease (PD)
Conditions
Keywords
Parkinson Disease, Dual-Task Training, Upper Extremity Function, Muscle Thickness, Ultrasonography
Brief summary
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease. The main questions it aims to answer are: Does dual-task training improve upper extremity function in individuals with Parkinson's disease? Does dual-task training lead to changes in upper extremity muscle thickness measured by ultrasonography? Researchers will compare a dual-task training group with a control group receiving routine care to determine whether 8 weeks of dual-task training results in greater improvements in upper extremity outco Participants will: complete baseline and post-intervention assessments of upper extremity function, muscle thickness, grip strength, and pinch strength be assigned to either a control group or a dual-task training group receive dual-task training 3 days per week for 8 weeks if assigned to the intervention group
Interventions
BEHAVIORALDual-Task Training
Dual-task training will be applied 3 times per week for 8 weeks, with each session lasting 60 minutes. The program combines motor tasks (such as peg placement, object manipulation, bilateral coordination, and mobility tasks) with simultaneous cognitive tasks (such as backward counting, category-based word generation, and memory tasks).
Sponsors
Ankara University
Hacettepe University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Participants will be randomly assigned to either a dual-task training group or a control group using block randomization. The dual-task training group will receive a structured exercise program consisting of combined motor and cognitive tasks, performed 3 times per week for 8 weeks, in addition to their usual daily activities. The control group will continue their routine daily life without receiving any additional intervention. Outcome assessments will be conducted at baseline and after 8 weeks by a blinded evaluator.
Eligibility
Sex/Gender
ALL
Age
40 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of idiopathic Parkinson's disease confirmed by a neurologist * Modified Hoehn and Yahr stage 2 to 3 * No medication or dosage change within the last 6 months * Cognitive capacity sufficient to understand and follow instructions, defined as Montreal Cognitive Assessment score ≥21 * Voluntary participation with written informed consent
Exclusion criteria
* Atypical or secondary parkinsonism * Advanced orthopedic condition affecting the upper extremity * Surgery, trauma, or immobilization involving the upper extremity within the last 6 months * Wound or dermatological condition preventing upper extremity ultrasonographic evaluation * Severe visual or hearing loss * Severe depression, psychosis, or communication difficulty * Any additional health problem preventing regular participation in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Upper Extremity Function | Baseline and 8 weeks | Upper extremity function will be assessed using the Purdue Pegboard Test. Performance will be recorded as the number of pins placed within the specified time for dominant hand, nondominant hand, and both hands; higher scores indicate better fine motor performance and manual dexterity. |
| Upper Extremity Muscle Thickness | Baseline and 8 weeks | Muscle thickness of the deltoid, biceps brachii, triceps brachii, and forearm flexor muscles will be measured using ultrasonography. The mean of three repeated measurements for each site will be recorded in millimeters. |
| Hand Grip Strength | Baseline and 8 weeks | Hand grip strength will be measured using a Jamar hydraulic hand dynamometer according to the ASHT protocol. The mean of three trials will be recorded. |
| Pinch Strength | Baseline and 8 weeks | Lateral pinch, three-jaw chuck pinch, and two-point pinch strength will be assessed using a pinch meter. The mean of three trials will be recorded in kilograms or Newtons. |
Countries
Turkey (Türkiye)
Contacts
CONTACTBüşra Seçkinoğulları Korkusuz, PhD
PRINCIPAL_INVESTIGATORBüşra Seçkinoğulları Korkusuz
Ankara University
STUDY_CHAIRSüleyman Korkusuz
Atılım University
STUDY_CHAIRAyşenur Özcan
Çankırı Karatekin University
STUDY_CHAIRAyla Fil
Hacettepe University
STUDY_CHAIRGül Yalçın Çakmaklı
Hacettepe University
Outcome results
None listed