The Prognostic Value of Cardiopulmonary Exercise Testing Parameters in Patients With Coronary Heart Disease: A Retrospective Cohort Study(CPETPCAD)

The Prognostic Value of Cardiopulmonary Exercise Testing Parameters in Patients With Coronary Heart Disease: A Retrospective Cohort Study

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07534410

Acronym

CPET-PCHD

Enrollment

15000

Registered

2026-04-16

Start date

2026-04-07

Completion date

2027-06-30

Last updated

2026-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Heart Disease (CHD)

Brief summary

Parameters related to cardiopulmonary exercise testing (CPET) are important objective indicators for evaluating cardiopulmonary function in patients with coronary heart disease. However, the clinical application of CPET parameters in the prognostic assessment of patients with coronary heart disease remains unclear. This is a retrospective cohort study designed to systematically collect real-world clinical data and long-term follow-up outcomes of patients with coronary heart disease. Through standardized follow-up, this study will investigate the association between CPET parameters and adverse clinical outcomes in patients with coronary heart disease, as well as the relevant risk factors.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

1. Our hospital has diagnosed coronary heart disease and conducted cardiopulmonary exercise tests. 2. Patients with complete clinical data.

Exclusion criteria

1. Uncontrolled heart failure (NYHA classification Ⅲ-IV grade). 2. Complications, such as moderate to severe anemia, tumors and lung diseases. 3. Complicated with valvular heart disease. 4. Unable to reach the anaerobic threshold during exercise.

Design outcomes

Primary

Measure	Time frame	Description
Cumulative incidence of Major Adverse Cardiovascular Events (MACE)	1 year	The proportion of patients who experience an adjudicated Major Adverse Cardiovascular Event (MACE), defined as a composite endpoint consisting of non-fatal myocardial infarction, non-fata

Secondary

Measure	Time frame	Description
All-cause mortality	1 year	Record of deaths from any cause during follow-up. Confirmed by medical records, family follow-up, or national death registration systems.

Contacts

CONTACTXiang Xie, PhD

xiangxie999@sina.com+86-991-4366892

STUDY_CHAIRXiang Xie, PhD

First Affiliated Hospital of Xinjiang Medical University

Outcome results