Axillary Block, Dexamethasone, Ibuprofen, Hand Surgery, Forearm Surgery, Postoperative Analgesia
Conditions
Keywords
Axillary Brachial Plexus Blockade, Hand and Forearm Surgery, Postoperative Analgesia, Intravenous Dexamethasone, Intravenous Ibuprofen
Brief summary
This study aims to comparatively examine the effects of preemptive intravenous dexamethasone and intravenous ibuprofen use on the duration of analgesia in ultrasound-guided Axillary Brachial Plexus Block applications for patients undergoing hand and forearm surgery. Furthermore, investigating the relationship between the study drugs and the incidence of Postoperative Nausea and Vomiting and determining the time until the first use of rescue analgesic are also among the secondary objectives.
Interventions
DRUGiv ibuprofen
Patients who are in group I had intravenouse 400 mg ibuprofen before axillary brachial plexus blockade.
Patients who are in group D had intravenouse 8 mg dexamethasone before axillary brachial plexus blockade.
Sponsors
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patient's consent to participate in the study (Informed consent) * Aged between 18 and 65 years * ASA physical status I or II * Being oriented and cooperative * Scheduled to undergo hand or forearm surgery * Body Mass Index (BMI) below 40 kg/m² * Scheduled for axillary brachial plexus blockade
Exclusion criteria
* Patient's refusal to participate in the study * Refusal of regional anesthesia * Known allergy to local anesthetics * Known allergy to ibuprofen * Known allergy to dexamethasone * Presence of coagulopathy * Local infection at the site of regional anesthesia application * Presence of malignancy at the surgical site * Diagnosis of diabetes mellitus * Body Mass Index (BMI) of 40 kg/m² or above * Duration of surgery exceeding 4 hours * Administration of opioid medication during the preoperative or intraoperative period
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of analgesia | 24 hours | Duration of analgesia was defined as the time from the performance of the block until the patient's first report of pain. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of PONV | 24 hours | The incidence of PONV during the first 24 hours following the block administration will be evaluated. |
Countries
Turkey (Türkiye)
Outcome results
None listed