Registry Analysis of Deceased Donor Kidney Transplant Outcomes

Registry Analysis of Deceased Donor Kidney Transplant Outcomes With Normothermic Machine Perfusion (NMP)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07530991

Enrollment

3500

Registered

2026-04-15

Start date

2026-04-01

Completion date

2029-04-30

Last updated

2026-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normothermic Machine Perfusion (NMP) of Deceased Donor Kidneys

Keywords

NMP, Normothermic, Perfusion, Kidney

Brief summary

This study uses existing transplant data obtained from a national public donor registry operated by the Organ Procurement and Transplant Network (OPTN) under Health Resources and Services Agency (HRSA) to evaluate outcomes associated with normothermic machine perfusion (NMP) of deceased donor kidneys. Currently, there is no method to study NMP kidney outcomes using the National Scientific Registry for Transplant Recipients (SRTR) national public registry, because no data field exists to identify which kidneys received NMP.

Detailed description

This is a retrospective observational study using existing data from the Scientific Registry of Transplant Recipients (SRTR)/ Organ Procurement and Transplant Network (OPTN) public registry following a Research Plan approved by Health Resources & Services Agency (HRSA).

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

15 Years to No maximum

Healthy volunteers

Inclusion criteria

* Requires kidney transplantation

Exclusion criteria

* \> 15 years old

Design outcomes

Primary

Measure	Time frame	Description
Delayed Graft Function	7 days post-transplantation	Requirement for dialysis immediately post kidney transplantation
Delayed Graft Function (DGF)	7 days	Requirement for dialysis within 7 days post kidney transplantation

Secondary

Measure	Time frame	Description
Serum creatinine	Up to 3 years post-transplantation	Serum creatinine level

Countries

United States

Contacts

STUDY_CHAIRHenri Leuvenink, PhD

34 Lives, PBC

STUDY_CHAIRJacqueline Garonzik-Wang, MD, PhD

University of Alabama at Birmingham

Outcome results