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The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices

The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices: A Cross-sectional Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07530211
Enrollment
93
Registered
2026-04-15
Start date
2026-03-11
Completion date
2026-03-23
Last updated
2026-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implants, Peri-implantitis, Peri-implant Mucositis

Keywords

Diabetes Mellitus, Smoking, Cardiovascular Disease, Osteoporosis, Peri-implant Health

Brief summary

This cross-sectional study evaluates the impact of systemic risk factors, including diabetes mellitus, smoking, cardiovascular disease, and osteoporosis, on peri-implant health status and clinical indices. The study included 93 patients with a total of 314 implants that have been in function for at least three years. The primary goal is to determine how these systemic conditions influence the prevalence of peri-implant mucositis and peri-implantitis.

Detailed description

Clinical parameters, including Gingival Index (GI), Plaque Index (PI), and Probing Depth (PD), were measured using a standard periodontal probe. Radiographic assessments were performed to evaluate bone loss in accordance with European Periodontology Workshop guidelines. Peri-implant health status was categorized into three groups: healthy, peri-implant mucositis, and peri-implantitis. Data analysis was conducted using chi-square and Mann-Whitney U tests to examine the associations between systemic factors and peri-implant tissues.

Interventions

OTHERClinical and Radiographic Periodontal Assessment

Clinical parameters (Plaque Index, Gingival Index, Probing Depth) and radiographic assessments were performed for each patient to determine peri-implant health status

Sponsors

Inonu University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
27 Years to 72 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients with at least one dental implant in function for at least three years. * Patients aged between 27 and 72 years. * Availability of complete clinical and radiographic records.

Exclusion criteria

* Implants in function for less than 3 years. * Pregnancy or lactation. * History of radiation therapy in the head and neck region

Design outcomes

Primary

MeasureTime frameDescription
Prevalence of Peri-implant DiseasesMinimum 3 years post-loading veya At clinical assessment, at least 3 years after implant loadingDistribution of dental implants categorized into three status groups: healthy, peri-implant mucositis, and peri-implantitis based on clinical and radiographic criteria

Secondary

MeasureTime frameDescription
Gingival Index (GI)At least 3 years after implant loadingAssessment of Gingival Index (GI) to evaluate the inflammatory status of peri-implant tissues.
Plaque Index (PI)At least 3 years after implant loading.Assessment of Plaque Index (PI) to evaluate the plaque accumulation around peri-implant tissues.
Probing Depth (PD)At least 3 years after implant loading.Assessment of Probing Depth (PD) to evaluate the pocket depth around peri-implant tissues.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 16, 2026