Microbiota
Conditions
Brief summary
This randomized clinical trial evaluates the effect of a mango and chia-based beverage on gut microbiota modulation in 100 Paraguayan children aged 8-16 years with obesity. Participants will consume the intervention beverage for 6 weeks. Fecal samples will be collected before and after each intervention to analyze microbiota composition using 16S rRNA sequencing. This study aims to characterize the gut microbiota of Paraguayan children for the first time and assess whether this functional beverage can positively modulate intestinal bacteria as a potential strategy to address childhood obesity, which affects 1 in 3 school-age children in Paraguay.
Interventions
OTHERMango juice
Mango juice drink for 6 weeks 200 ml daily, 5 days a week
OTHERMango and chia juice
Mango and chia juice drink for 6 weeks, 200 ml daily 5 days a week
Sponsors
Universidad Nacional de Caaguazu
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
8 Years to 16 Years
Healthy volunteers
Yes
Inclusion criteria
100 children aged 8-16 years from Paraguay, stratified by BMI (with/without excess weight).
Exclusion criteria
Allergyc to mango or chia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Microbiota | Baseline and after 4 weeks | Gut microbiota composition analysis (16S rRNA sequencing) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anthropometric measurements | Baseline and after 4 weeks | Measure of weight |
Countries
Paraguay
Contacts
CONTACTJulieta Mendez, Msc
Outcome results
None listed