COVID-19
Conditions
Brief summary
The purpose of this research is to find out if Positron Emission Tomography (PET) imaging with an investigational drug called C-11 ER176 can help us learn more about Post-COVID Syndrome.
Interventions
DRUGC11 ER176 Tracer
C11 ER176 tracer will be administered by IV, followed by PET imaging of the brain to evaluate for neuroinflammation
Sponsors
Mayo Clinic
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Mayo Clinic patients with a previously confirmed infection with the novel SARS-CoV-2 virus who have been seen in the Post COVID Clinic through GIM Integrative Medicine \& Health Section or approval by MAGPIES research group. * Be able to participate fully in all aspects of the study. * Have understood and signed study informed consent.
Exclusion criteria
* Lacking the capacity to consent. * Prisoners and institutionalized individuals. * Reports being currently pregnant, lactating, or are of child-bearing potential or are likely to become pregnant during the LLLT treatment phase and are unwilling to use a reliable form of contraception. o Acceptable forms include: * Hormonal methods, such as birth control pills, patches, injections, vaginal ring, or implants * Barrier methods (such as a condom or diaphragm) used with a spermicide (a foam, cream, or gel that kills sperm) * Intrauterine device (IUD) * Total hysterectomy or tubal ligation * Abstinence (no sex). * Those patients that have implants that would prevent them from having a PET Scan. * Patients that have claustrophobia. * Have a known history of any condition or factor judged by the investigator to preclude participation in the study or which might hinder adherence.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Degree of Neuroinflammation | Baseline reading only | Estimation of areas degree of neuroinflammation determined by the radiologist |
Countries
United States
Contacts
CONTACTKatie Cruz
PRINCIPAL_INVESTIGATORRyan T. Hurt, MD, PhD
Mayo Clinic
Outcome results
None listed