Comparison of the Analgesic Efficacy of Adductor Canal Block and Combined Adductor Canal Block Plus IPACK Block in Knee Surgery

Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Block Combined With Local Anesthetic Infiltration Between the Popliteal Artery and the Capsule of the Knee (IPACK) in Patients Undergoing Knee Surgery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07526831

Enrollment

Registered

2026-04-13

Start date

2026-04-15

Completion date

2028-05-01

Last updated

2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthroplasty, Total

Keywords

ultrasound, IPACK block, Adductor Canal Block

Brief summary

To evaluate the effectiveness of Adductor Canal Block and combined Adductor Canal plus IPACK block in reducing postoperative pain and analgesic requirements in patients undergoing knee surgery.

Detailed description

In total knee arthroplasty, ultrasound-guided Adductor canal block or Adductor Canal block combined with local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK) will provide adequate postoperative analgesia.

Interventions

PROCEDUREAdductor Canal Block Group (Group I)

All patients in Group I will receive a preoperative adductor canal block. In all groups, an intravenous patient-controlled analgesia device containing morphine will be administered for postoperative pain management.

PROCEDUREAdductor Canal + iPACK Block Group (Group II)"

All patients in Group II will receive a preoperative adductor canal block combined with an iPACK block. Postoperatively, all patients in both groups will be provided with intravenous patient-controlled analgesia containing morphine for pain management.

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ASA (American Society of Anesthesiologists) I- ASA II-ASA III Patients

Exclusion criteria

* history of allergy to the study medication * refusal to participate

Design outcomes

Primary

Measure	Time frame	Description
opioid consumption	24 hours after surgery	In the recovery room, all patients will given a patient- controlled analgesia device containing morphine 0.5 mg/ml, set to deliver a 1mg bolus dose of morphine with an 15 min lockout time and 4 mg 1 h limit.Total morphine consumption during the 24 hours postoperative period will recorded at 5 times intervals ( 2, 4, 6, 12, 24 hours).
Verbal analog Pain Scores on rest and movement	24 hours after surgery	A Research assistant, blinded to the group allocation, interviewed patients and collected data at 5 times intervals ( 2, 4, 6, 12, 24, hours) in the 24 hours postoperatively. Patients were asked to rate their pain using verbal analog scale, where 0= no pain and 10= worst pain possible.

Secondary

Measure	Time frame	Description
incidences of adverse effects (like nausea and vomiting)	24 hours after surgery	incidences of nausea and vomiting during the 24 hours postoperative period will recorded at 6 time intervals ( 2, 4, 6, 12, 24 hours).

Countries

Turkey (Türkiye)

Contacts

CONTACTSibel Pehlivan, DR

Sibelpehlivan@erciyes.edu.tr0905052532919

STUDY_DIRECTORSibel Pehlivan

Erciyes Üniversitesi

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 15, 2026