Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital

Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital: A Prospective Observational Cohort Study

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07526636

Enrollment

120

Registered

2026-04-13

Start date

2026-05-01

Completion date

2027-04-01

Last updated

2026-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hirschsprung Disease, Intestinal Atresia, Malrotation, Necrotizing Enterocolitis

Keywords

Neonate, NICU, Gastrointestinal emergency, Intestinal obstruction

Brief summary

This prospective observational study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonates admitted with gastrointestinal emergencies to the NICU at Assiut University Children Hospital. Data will be collected from admission through discharge, including demographic, antenatal, natal, clinical, nutritional, laboratory, and radiological information, to identify the most common emergencies and factors associated with adverse outcomes.

Detailed description

This prospective observational cohort study will be conducted at the Neonatal Intensive Care Unit (NICU) of Assiut University Children Hospital. The study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonatal gastrointestinal emergencies. Eligible neonates will be enrolled consecutively from admission until discharge. Both term and preterm neonates will be included. Data will be systematically collected on demographic characteristics, antenatal and natal history, clinical presentation, feeding practices, laboratory investigations, and radiological findings. Management approaches, including medical and surgical interventions, will be documented. Patients will be followed throughout their hospital stay to assess outcomes, including recovery, complications, need for surgical intervention, and mortality. The study also aims to identify the most common types of gastrointestinal emergencies and determine the clinical and demographic factors associated with adverse outcomes among affected neonates.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Years to 28 Days

Inclusion criteria

* Neonates aged 0-28 days (corrected age if preterm) * Admitted to the NICU with a clinical diagnosis of a gastrointestinal emergency requiring urgent intervention * Written informed consent obtained from parent(s) or legal guardian(s)

Exclusion criteria

* Other gastrointestinal problems not requiring urgent intervention

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of the most common gastrointestinal emergencies among neonates admitted to the NICU	Up to 28 days (hospital stay)	The prevalence of each type of neonatal gastrointestinal emergency will be calculated as the proportion of cases among all enrolled neonates admitted to the NICU during the study period. Diagnoses will be based on clinical, laboratory, and radiological findings.

Secondary

Measure	Time frame	Description
Mortality Rate	Up to 28 days (hospital stay	Proportion of neonates who die during hospitalization
Length of Hospital Stay	From admission to discharge, up to 28 days	Duration of hospitalization in days from NICU admission until discharge or death
Requirement for surgical intervention	During hospitalization, up to 28 days	The proportion of neonates requiring surgical management among the enrolled cases.

Outcome results