Stroke, Rehabilitation, Virtual Reality, Mirror Movement Therapy, Attention, Task Performance
Conditions
Brief summary
In this study, we hypothesized that Virtual Reality Mirror Therapy with Focused Object-Directed Attention (VRMTFOA) would yield superior therapeutic effects compared to conventional Virtual Reality Mirror Therapy (VRMT) in individuals with unilateral stroke. The aim of this study is to compare the immediate effects of a single session of VRMT, VRMTFOA, and VRMTFOA with auditory feedback on upper extremity function and brain activity in stroke patients.
Interventions
Motor training targeted to goals that are relevant to the functional needs of the patient
Sponsors
National Cheng-Kung University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Clinical diagnosis of stroke with unilateral side involved; A score of Mini-mental state examination greater than 24 for proving higher mental function; Time of onset \> 6 months before treatment begins; and Premorbid right-handedness.
Exclusion criteria
* Severe vision impairment; Major cognitive-perceptual deficit; Other brain disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the result of Fugl-Meyer assessment (FMA) for motor function of upper extremity test | baseline, 9 weeks and 21 weeks | Each item is rated on a three-point ordinal scale (2 points for the detail being performed completely, 1 point for the detail being performed partially, and 0 for the detail not being performed). The maximum motor performance score is 66 points for the upper extremity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in the result of Modified Ashworth scale (MAS) | baseline, 9 weeks and 21 weeks | Muscle tone is defined by assess muscle tone by evaluating resistance to passive stretch, reflecting the level of spasticity, with scores ranging from 0 (no increase in tone) to 4 (rigidity in flexion or extension). |
| Change in the result of Box and blocks test | baseline, 9 weeks and 21 weeks | The score is the number of blocks carried from one box to the other in one minute. Higher values represent a better outcome. |
| Change in the result of Semmes-Weinstein monofilament (SWM) test | baseline, 9 weeks and 21 weeks | The Semmes-Weinstein monofilamenttest examines the cutaneous pressure threshold, range from 1.65-6.65. Higher values represent a worse outcome. |
| Change in the result of Motor Activity Log | baseline, 9 weeks and 21 weeks | Semi-structured interview examine how much and how well the subject uses their more-affected arm for 30 ADLs. Score range from 0-5. Higher values represent a better outcome. |
| Surface electromyography (sEMG) | baseline, 9 weeks | Change in the root mean square (RMS) of the EMG signal was computed to quantify the change of muscle activation. |
| Clinical Global Impression (CGI) scale | 9 weeks | Assess overall clinical change, rated on a 7-point scale ranging from 1 (very much improved) to 7 (very much worse). |
Countries
Taiwan
Contacts
CONTACTHsiu-Yun Hsu, Ph.D
Outcome results
None listed