Wound Heal
Conditions
Brief summary
This study aims to evaluate the efficacy of VSD in promoting wound healing and reducing complications, such as re-infection, prolonged hospitalization, and need for further surgical interventions, in obstetric and gynecological patients who have developed surgical site infections following their primary procedures. The investigators hypothesize that VSD will lead to faster wound healing, fewer complications, and improved patient outcomes compared to conventional wound care in this specific patient population.
Interventions
BIOLOGICALConventional Wound Care Group
o Wounds will be managed with daily or twice-daily dressing changes using saline-moistened gauze, antiseptic solutions, and sterile dry dressings, as per standard hospital protocols for infected wounds
BIOLOGICALVacuum Sealing Drainage (VSD) Group
After initial debridement, a VSD system will be applied to the wound bed. The wound will be sealed with an adhesive drape, and connected to a negative pressure unit.
Sponsors
Minia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of a surgical site infection (SSI) following an obstetric or gynecological surgical procedure (e.g., Cesarean section, hysterectomy, myomectomy, salpingo-oophorectomy). * Wound classification as superficial incisional SSI, deep incisional SSI, or organ/space SSI (if accessible for VSD application). * Willingness and ability to provide informed consent. * Wound requiring secondary intention healing or delayed primary closure after debridement
Exclusion criteria
* Patients with necrotic tissue. * Presence of exposed blood vessels, organs, or anastomotic sites where VSD is contraindicated. * Untreated coagulopathy or active bleeding diathesis. * Allergy to VSD components or dressing materials. * Patients with significant immunosuppression (e.g., uncontrolled HIV, organ transplant recipients on high-dose immunosuppressants). * Patients with malignant wounds. * Patients who decline participation. * Patients requiring immediate primary wound closure without debridement. * Patients with a known history of severe psychiatric illness affecting compliance.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to complete wound healing | weekly follow up for one month after procedure | Defined as complete epithelialization of the wound, measured in days |
Countries
Egypt
Contacts
CONTACTMohamed abdel ghfar
Outcome results
None listed