Surgery
Conditions
Brief summary
The purpose of this study is to compare the mean cumulative weight-based/time-corrected rocuronium dose administered in patients undergoing robotic- or laparoscopic- assisted surgery using either acceleromyography or electromyography.
Interventions
DEVICEAMG device
The anesthesia team will use an AMG device to monitor neuromuscular block
DEVICEEMG
The anesthesia team will use an EMG device to monitor neuromuscular block
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \> or = 18 years old * Patients willing to participate and provide an integrated, informed consent * Patients undergoing elective laparoscopic- or robotic-assisted surgical procedures * Anticipated surgery duration \< 300 minutes
Exclusion criteria
* Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury. * Patients with systemic neuromuscular diseases such as myasthenia gravis. * Patients having surgery that would involve prepping the arm into the sterile field. * Patients with chronic kidney disease (eGFR \<60).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cumulative rocuronium dose | Perioperative/Periprocedural | Weight- and time-adjusted mean cumulative rocuronium dose between the AMG and EMG groups |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mean sugammadex dose | Perioperative/Periprocedural | Mean sugammadex dose between the two groups |
| Number of rocuronium administrations | Perioperative/Periprocedural | Number of rocuronium administrations throughout the case, |
| Frequency of placing a peripheral nerve stimulator | Perioperative/Periprocedural | Frequency of placing a peripheral nerve stimulator |
| Depth of neuromuscular block prior to sugammadex administration | Perioperative/Periprocedural | Depth of neuromuscular block prior to sugammadex administration |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORJohnathan Renew
Mayo Clinic
Outcome results
None listed