Video-EEG Features of Adult Patients With Psychogenic Nonepileptic Seizures

Retrospective Analysis of Video-EEG Findings and Clinical Characteristics in Adult Patients With Psychogenic Nonepileptic Seizures

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07521761

Enrollment

Registered

2026-04-13

Start date

2026-01-01

Completion date

2026-03-01

Last updated

2026-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychogenic Nonepileptic Seizures

Brief summary

This completed retrospective observational study evaluated adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring. Video-EEG records and clinical data of 50 adult patients were reviewed to describe semiological, electroclinical, and demographic characteristics of PNES. The study aimed to improve the understanding of video-EEG findings in PNES and to support accurate diagnosis in clinical practice.

Detailed description

Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on EEG. Video-EEG monitoring is considered the reference standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical files of 50 adult patients with PNES were reviewed after completion of clinical care. Demographic data, clinical presentation, and video-EEG characteristics were analyzed descriptively. No intervention was assigned as part of the study. The purpose was to characterize the video-EEG and clinical profile of adult PNES patients evaluated in routine practice.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults aged 18 years and older Diagnosis of psychogenic nonepileptic seizures based on video-EEG evaluation Availability of complete video-EEG recordings and relevant clinical records for review

Exclusion criteria

* Patients younger than 18 years Inadequate or incomplete video-EEG data Patients with insufficient clinical documentation for retrospective evaluation

Design outcomes

Primary

Measure	Time frame	Description
Semiological subtype of PNES events	Baseline retrospective chart and video-EEG review	Classification of PNES events recorded during video-EEG monitoring into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features.

Secondary

Measure	Time frame	Description
Presence/absence of some events during PNES events	Baseline	Eye closure during PNES events Hyperventilation during PNES events Hyperkinetic motor activity Axial extension Pelvic thrusting

Countries

Turkey (Türkiye)

Outcome results