Cesarean Section, Cortisol, Preoperative Anxiety, Surgical Stress Response
Conditions
Keywords
Preoperative Anxiety, Cesarean Delivery, Cortisol Biomarker
Brief summary
Preoperative anxiety is a common problem in patients undergoing elective cesarean section and may negatively affect perioperative outcomes through activation of the stress response, including increased cortisol levels. Effective preoperative information is considered a key non-pharmacological strategy to reduce anxiety; however, the optimal method of information delivery remains unclear. This prospective randomized controlled trial aims to compare the effects of video-based versus verbal preoperative information on anxiety levels and serum cortisol response in patients scheduled for elective cesarean delivery under spinal anesthesia. Anxiety will be assessed using the State-Trait Anxiety Inventory (STAI), and serum cortisol levels will be measured before and after the intervention. The findings of this study are expected to provide evidence for improving patient-centered preoperative education strategies in obstetric anesthesia."
Interventions
BEHAVIORALVerbal Preoperative Information
Participants will receive standard preoperative information about anesthesia and the surgical procedure through face-to-face verbal communication delivered by an anesthesiologist according to routine clinical practice at least one hour before surgery.
BEHAVIORALVideo-Based Preoperative Information
Participants will receive standardized video-based preoperative information covering anesthesia and the surgical procedure at least one hour before surgery. The content of the video will be equivalent to the verbal information provided in routine clinical practice.
Sponsors
Elazıg Fethi Sekin Sehir Hastanesi
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Pregnant women aged 18 years or older * Scheduled for elective cesarean delivery * Planned to receive spinal anesthesia * American Society of Anesthesiologists (ASA) physical status I-II * Ability to provide written informed consent
Exclusion criteria
* Emergency cesarean delivery * History of psychiatric disorders * Current use of anxiolytic or antidepressant medications * Endocrine disorders, particularly adrenal or thyroid disease * Current corticosteroid therapy * History of previous surgery under spinal anesthesia * Cognitive impairment preventing effective communication or completion of the assessment scales * American Society of Anesthesiologists (ASA) physical status III-V
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in preoperative anxiety level measured by the State-Trait Anxiety Inventory (STAI-S) | Immediately before preoperative information and approximately 1 hour after preoperative information, before surgery | Change in preoperative anxiety level measured by the State-Trait Anxiety Inventory-State (STAI-S), a 20-item scale with scores ranging from 20 to 80, where higher scores indicate greater anxiety. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum cortisol level change | Immediately before preoperative information and approximately 1 hour after preoperative information, before surgery | Change in serum cortisol levels measured from venous blood samples obtained immediately before preoperative information and approximately 1 hour after preoperative information, before surgery. |
Countries
Turkey (Türkiye)
Outcome results
None listed