Class I Malocclusion, Maxillary Prognathism, Orthodontic Tooth Movement
Conditions
Brief summary
study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.
Detailed description
Silver-hydroxyapatite nanoparticles (Ag-HA NPs) have lately gained popularity in dentistry due to their unique combination of silver antibacterial activity and hydroxyapatite's osteoconductive, remineralizing characteristics. Ag-HA has shown potential in resolving two important clinical issues: infection control and anchoring stability. Coating orthodontic miniscrews with Ag-HA NPs has been demonstrated to reduce peri-implant biofilm growth by their antimicrobial effect, minimizing inflammation, and increasing osseointegration, thus increasing the long-term success of temporary anchoring devices (TADs).
Interventions
DEVICESilver nanoparticles
Patients will receive silver-hydroxyapatite nanocoated titanium miniscrews.These miniscrews will be placed in the maxillary bone for en masse retractonof the upper anterior teeth.
DEVICEuncoated titanium miniscrews
Patients will receive conventional uncoated titanium miniscrews of the same dimensions and design as the intervention of the group1, but without nano-coating.
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
14 Years to 20 Years
Healthy volunteers
No
Inclusion criteria
* Class I orthodontic cases with bimaxillary protrusion of the anterior segment of the upper jaw that need at least extraction for orthodontic treatment. * Age 14-20 years. * Good oral hygiene with healthy periodontium. * Need for an absolute skeletal anchorage. * Systemically healthy patients.
Exclusion criteria
* Patient with craniofacial anomalies (e.g, cleft lip and palate) * Presence of systemic diseases or syndromes affecting bone metabolism (e.g, osteoporosis, rickets) * Poor oral hygiene or uncooperative patients. * Extensive dental caries or untreated periodontal disease. * History of trauma or surgery affecting the maxilla or mandible.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of the clinical and radiographically success rate of nanocoated versus uncoated orthodontic miniscrews after en masse retraction | about 6 months | Assessment of the clinical and radiographically success rate of nanocoated versus uncoated orthodontic miniscrews after en masse retraction |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of the rate of en masse retraction of the anterior segment of the upper arch | 6 months | Assessment of the rate of en masse retraction of the anterior segment of the upper arch. |
Countries
Egypt
Contacts
CONTACTHashem Kh Al-Washali, MScCandidate
CONTACTMahmoud FA Aboelmahasen, Phd
STUDY_DIRECTORMahmoud FA Aboelmahasen, Phd
Faculty of Dental Medicine (Boys), Al-Azhar University, Cairo, Egypt
STUDY_DIRECTORAhmed Ak El-Awady, Phd
Faculty of Dental Medicine (Boys), Al-Azhar University, Cairo, Egypt
Outcome results
None listed