Immediate Implant Placement Using Socket Shield With CGF

Clinical and Radiographic Evaluation of Concentrated Growth Factors With Simultaneous Immediate Implant Placement in Socket Shield Technique

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07520526

Acronym

CGF

Enrollment

Registered

2026-04-09

Start date

2026-04-01

Completion date

2026-12-30

Last updated

2026-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar Bone Loss, Alveolar Bone Preservation, Concentrated Growth Factors, Immediate Dental Implant Placement, Socket Shield Technique

Keywords

Socket shield technique, immediate implants, concentrated growth factor

Brief summary

This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic zone. Outcomes will include crestal bone level changes assessed by CBCT and implant stability measured using Osstell.

Detailed description

This prospective case series study will be conducted to evaluate clinically and radiographically the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) during immediate implant placement in the esthetic zone. Eligible patients requiring extraction and immediate implant placement in the maxillary anterior or premolar region will be included. Following atraumatic extraction, partial extraction therapy using the socket shield technique will be performed, leaving the buccal root fragment in place. Implant osteotomy and placement will then be carried out according to manufacturer instructions. Autologous concentrated growth factors will be prepared from the patient's blood using a CGF centrifugation protocol. The CGF gel will be packed into the jumping gap between the implant and socket wall to promote bone regeneration and healing. Clinical and radiographic evaluation will be performed using CBCT at baseline, 2 weeks, and 6 months postoperatively. The primary outcome will be crestal bone level changes measured radiographically, while the secondary outcome will include implant stability assessed using Osstell measurements (ISQ values). Seven participants will be recruited in this case series. Follow-up will be conducted to evaluate healing, bone remodeling, and implant stability.

Interventions

PROCEDUREImmediate implant placement with Socket Shield Technique and CGF

Partial extraction therapy using the socket shield technique followed by immediate implant placement. Concentrated growth factors prepared from autologous blood will be packed in the jumping gap to enhance bone regeneration and healing.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥18 years old. (Younis, W., \& El-Rashidy, A. 2020). * Both male and female patients. * Maxillary, anterior and premolar segment.

Exclusion criteria

* A medical history that contraindicates oral surgical treatment such as (uncontrolled/untreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and/or intravenous bisphosphonates). * Presence of active or untreated periodontal disease. * Vertical root fractures involving the buccal aspect. * Tooth /teeth with horizontal fractures below bone level. * Tooth /teeth with external or internal resorption. * Patients with destructive oral habits such as smoking, chewing tobacco, bruxism, etcetera.

Design outcomes

Primary

Measure	Time frame	Description
Crestal bone level	2 weeks and 6 months post-operatively	Radiographic evaluation of crestal bone level changes around the implant using CBCT, measured in millimeters (mm).

Secondary

Measure	Time frame	Description
Implant stability	Immediately after implant placement and at 6 months	Implant stability will be assessed using resonance frequency analysis with the Osstell device and recorded as Implant Stability Quotient (ISQ). ISQ values range from 1 to 100, where higher values indicate greater implant stability and a better outcome.

Countries

Egypt

Contacts

CONTACTAreej Khalid Rasheid, bachelors

areej.rashyd@dentistry.cu.edu.eg+201033903216

STUDY_CHAIRTarek I.A El-Ghareeb, PHD Holder

Cairo University

STUDY_DIRECTORAbdelmoez Mohamed El-Sharkawy, Associate professor