Condylar Offset and Outcomes in Primary Total Knee Arthroplasty

Prospective Evaluation of Posterior and Anterior Condylar Offset and Their Impact on Functional Outcomes in Primary Total Knee Arthroplasty

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07517614

Acronym

OFFSET-TKA

Enrollment

100

Registered

2026-04-08

Start date

2026-05-01

Completion date

2027-07-01

Last updated

2026-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthritis Osteoarthritis

Keywords

knee osteoarthiritis, anterior condylar offset, posterior condylar offset

Brief summary

This prospective cohort study aims to evaluate the effect of posterior condylar offset (PCO) and anterior condylar offset (ACO) changes on functional outcomes after primary total knee arthroplasty (TKA). Standardized imaging and clinical assessment protocols will be used to determine optimal PCO and ACO ranges associated with improved postoperative range of motion, patient-reported outcomes, and reduced anterior knee symptoms.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to 85 Years

Healthy volunteers

Inclusion criteria

* diagnosis of primary knee osteoarthiritis * indication of knee arthroplasty * 50-85 years * ability t oprovide informed consent and comply with follow up

Exclusion criteria

* revision knee arthroplasty * inflammatory arthritis * severe corona deformity (\>20 varus/valgus) * previous knee surgery or fracture

Design outcomes

Primary

Measure	Time frame	Description
Maximum Knee Flexion	12 months postoperatively	maximum active knee flexion measured in degrees using a goniometer during clinical examination

Secondary

Measure	Time frame	Description
Knee Society Score	3,6,12 months postoperatively	The Knee Society Score (KSS) is a clinician-reported outcome measure consisting of two components: the Knee Score (pain, stability, and range of motion) and the Function Score (walking distance and stair climbing). Each component ranges from 0 to 100, with a total possible score of 200. Higher scores indicate better knee function and clinical outcomes.
WOMAC score	3,6,12 months postoperatively	The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a patient-reported outcome measure assessing pain, stiffness, and physical function. The total score ranges from 0 to 96, with higher scores indicating worse pain, stiffness, and functional limitation.
Change in Anterior and Posterior Condylar Offset	preoperative graphy and postoperative 1st day graphy	difference between preoperative and postoperative 1st day anterior condylar offset mesaured on lateral knee radiographs

Outcome results