Light, Anesthesia, Sedation
Conditions
Keywords
light, anesthesia, sedation depth
Brief summary
The objective of this clinical trial is to investigate the effect of light exposure on sedation depth during general anesthesia.The primary research questions this study aims to address include: Does light condition affect the dosage of anesthetic medications during anesthesia? By what mechanism does light exposure exert an influence on anesthesia? Participants will be randomly allocated to either the light-shielded group or the non-light-shielded group.Patients in the light-shielded group will wear an eye shield during anesthesia. The following data will be recorded for all patients: Induction drug dosage Induction time Intraoperative anesthetic dosage Emergence time
Interventions
DEVICEeye mask
Patients in the light-shielded group will wear an opaque eye mask 30 minutes prior to induction of general anesthesia and continue to do so until the cessation of sedative medications for anesthesia.
Sponsors
Peking University People's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Masking description
Data analyst
Eligibility
Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* a. Age between 18 and 65 years, regardless of gender; * b. ASA physical status I-II; * c. 18.5 ≤ BMI ≤ 28; * d. Signed written informed consent.
Exclusion criteria
* a. Blindness or history of photosensitivity disorders; * b. Patients requiring medication for sleep, or with a history of sleep disorders; * c. Presence of neurological diseases; * d. Pregnancy; * e. Severe hepatic or renal dysfunction; * f. History of anesthetic drug abuse or alcohol abuse; * g. History of adverse anesthesia events (difficult airway, allergy to anesthetic agents).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The dose of sedative medications | Perioperative | The dose of sedative medications required during the induction period in patients |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Induction time of anesthesia | Perioperative | Induction time of anesthesia |
| total dose of sedative medications | during surgery | total dose of sedative medications required to maintain a certain range of anesthetic depth during surgery |
| emergence time | Perioperative | emergence time after drug discontinuation |
Countries
China
Contacts
CONTACTYi Feng, Ph.D
CONTACTXiaoyan Li, Ph.D
Outcome results
None listed