Orthodontic Treatment Efficiency
Conditions
Keywords
Orthodontics Malocclusion Corticision
Brief summary
biological assesment during intrusion of lower incisors
Detailed description
Assessment of the biological response of the corticision during intrusion of lower incisors A prospective clinical study
Interventions
OTHERCorticision
1. Prior panoramic x-ray or serial periapical x-rays are essential to assure the availability of interradicular room to carry out the procedure. 2. Preoperative antiseptic mouthwash is administered to prevent potential infections. 3. Infiltration anesthesia is applied. 4. A reinforced 15T scalpel is positioned on the interradicular attached gingiva at an inclination of 45-60 degrees on the long axis of the tooth to be moved.
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
14 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients requiring extraction-based orthodontic treatment * Presence of deep overbite requiring lower incisor intrusion * Age range: 18-30 years * Good general health * Good oral hygiene
Exclusion criteria
* Systemic diseases affecting bone metabolism * Previous orthodontic treatment * Periodontal disease * Smoking * Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gingival crevicular fluid (GCF) prostaglandin E2 (PGE2) levels measured by enzyme-linked immunosorbent assay (ELISA) (pg/mL) | 12 weeks | GCF samples will be collected from lower incisors using microcapillary tubes at baseline and during follow-up visits. Prostaglandin E2 levels will be quantified using ELISA kits and expressed in pg/mL to assess the biological response to corticision-assisted intrusion. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Amount of lower incisor intrusion measured in millimeters (mm) using cone beam computed tomography (CBCT) | 12 weeks | CBCT imaging will be used to measure the vertical displacement of lower incisors in millimeters by comparing pre- and post-treatment positions. |
| External apical root resorption measured in millimeters (mm) using cone beam computed tomography (CBCT) | Time Frame: 12 weeks | CBCT imaging will be used to assess external apical root resorption by comparing root lengths before and after treatment. |
Contacts
CONTACTalaa eldin elshahat shafay, post gradute student
CONTACTMahmoud Fathy Aboelmahasen, lecturer
STUDY_DIRECTORRamadan Yu Abu-shahba, professor
Al-Azhar University, Faculty of Dental Medicine
Outcome results
None listed