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Gastric Volume and Fasting Duration in Pregnant Women

Comparison of Gastric Volume Measured by Ultrasonography According to Preoperative Fasting Duration in Pregnant Women Undergoing Elective Cesarean Section and Evaluation of Influencing Factors

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07513675
Acronym
PREG-GAS
Enrollment
90
Registered
2026-04-07
Start date
2024-06-01
Completion date
2025-06-01
Last updated
2026-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ceserean Section, Gastric Volume, Postoperative Nausea and Vomit, Pregnancy

Keywords

gastric ultrasound, fasting duration, gastric volume, antral cross-sectional area, aspiration risk, obstetric anesthesia, Cesarean section

Brief summary

This prospective observational study aimed to evaluate the effect of preoperative fasting duration on gastric volume and antral visibility in pregnant women undergoing elective cesarean section. Patients were divided into two groups according to fasting duration (6-8 hours and 8-10 hours), and preoperative gastric ultrasonography was performed to assess antral cross-sectional area and gastric volume. Additionally, the study investigated the relationship between gastric ultrasound findings and postoperative complications such as nausea and vomiting. The influence of demographic and clinical variables, including age, body mass index, ASA score, and fetal characteristics, on gastric volume was also evaluated.

Detailed description

This prospective observational study was conducted to evaluate the effect of preoperative fasting duration on gastric volume and antral visibility in pregnant women undergoing elective cesarean section. A total of 90 pregnant women were included in the study and divided into two groups based on fasting duration (6-8 hours and 8-10 hours). Preoperative gastric ultrasonography was performed in all patients to measure antral cross-sectional area and estimate gastric volume. Gastric content was also assessed using antral grading. Demographic and clinical data including age, body mass index, ASA physical status, comorbidities, and fetal characteristics were recorded. Postoperative outcomes such as nausea, vomiting, and aspiration were evaluated and their relationship with gastric ultrasound findings was analyzed. Additionally, factors affecting gastric volume were assessed using statistical models. The results of this study may contribute to improved perioperative risk stratification and individualized assessment of aspiration risk in obstetric anesthesia, and may help optimize preoperative fasting protocols.

Interventions

None listed

Sponsors

Dr. Lutfi Kirdar Kartal Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* Pregnant women aged 18-45 years Gestational age between 37-40 weeks Scheduled for elective cesarean section ASA physical status II-III Body mass index (BMI) \< 35 kg/m² Undergoing spinal anesthesia

Exclusion criteria

* BMI ≥ 35 kg/m² Emergency cesarean section Known gastrointestinal disease (e.g., gastroesophageal reflux disease) Use of medications affecting gastric motility History of gastric surgery Presence of infiltrative diseases (e.g., scleroderma, amyloidosis) Use of antiemetic drugs within 24 hours before surgery Severe hypertension during pregnancy (systolic \>160 mmHg or diastolic \>110 mmHg) Multiple pregnancy Patients who refused to participate

Design outcomes

Primary

MeasureTime frameDescription
Gastric Volume Measured by UltrasonographyPreoperative period (before anesthesia induction)Preoperative gastric volume measured using gastric ultrasonography in pregnant women undergoing elective cesarean section, and comparison between different fasting duration groups (6-8 hours vs 8-10 hours).

Secondary

MeasureTime frameDescription
Antral Cross-Sectional AreaPreoperative periodMeasurement of gastric antral cross-sectional area using ultrasonography and comparison between fasting duration groups.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 8, 2026