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Comparison Between Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine

Comparative Study of Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine : Clinical Outcomes and Neurophysiological Correlates A Prospective Randomized Study

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07512219
Enrollment
70
Registered
2026-04-06
Start date
2026-05-01
Completion date
2027-05-01
Last updated
2026-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Migraine, Headache

Brief summary

Comparative Study of Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine : Clinical Outcomes and Neurophysiological Correlates A Prospective Randomized Study

Interventions

DRUGGreater occiptal nerve block

Injection Procedure: 1. Local skin infiltration with 1-2 mL of 1% lidocaine at puncture site. 2. GON block using 3-5 mL of local anesthetic, optionally combined with 20-40 mg triamcinolone ( Bilaterally ) 3. Needle placement confirmed by ultrasound visualization of the nerve and spread of injectate. 4. Observe patient for 15-20 minutes post-injection for immediate adverse events.

DEVICEPulsed radiofrequency

1. Introduce RF cannula adjacent to GON under ultrasound guidance. 2. Confirm sensory stimulation: paresthesia at occipital scalp at \<0.5 V. 3. PRF settings: * Temperature: ≤42°C * Pulse duration: 20 ms * Frequency: 2 Hz * Duration: 120 seconds per cycle, 2 cycles per side 4. Continuous monitoring of patient comfort and vital signs.

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* patient with Diagnosis of chronic migraine for \> 3 months. * migraine days ≥ 15 days/month. * Failure or inadequate response to standard medical treatment.

Exclusion criteria

* Secondary headache disorders. * Coagulopathy or anticoagulant therapy. * Infection at injection site. * History of cervical spine surgery. * Pregnancy or breastfeeding. * Previous PRF or occipital nerve surgery within last 3 months

Design outcomes

Primary

MeasureTime frameDescription
The change in the VAS score of Pain over period of follow up6 monthsafter do GONB and Pulsed radio frequency we assess improvement of Episodic Pain over period of Follow up

Contacts

CONTACTshehab Mahmoud mohamed, assisstant lecturer
shehabmahmoud@med.sohag.edu.eg0201090442332

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 7, 2026