Tetanus, Manifest
Conditions
Keywords
Tetanus, Tetanus Severity Score
Brief summary
Three scoring systems will be applied to patients suffering from manifest tetanus and will be related to mortality.
Detailed description
On admission to the intensive care unit, three scoring systems for tetanus severity will be applied to all patients: the Tetanus Severity Score (TSS), Dakar Score, and Philips Score, and will then be related to the occurrence of in-hospital mortality or survival to hospital discharge.
Interventions
DIAGNOSTIC_TESTTetanus Severity Score (TSS)
The Tetanus Severity Score (TSS) is calculated for each patient by the investigator using the required data as documented in the medical records at admission
DIAGNOSTIC_TESTPhilips Score
The Philips Score is calculated for each patient by the investigator using the required data as documented in the medical records at admission
DIAGNOSTIC_TESTDakar Score
The Dakar Score is calculated for each patient by the investigator using the required data as documented in the medical records at admission
Sponsors
Ain Shams University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (age 18 years old or more). * Any sex (male or female), regardless of gender identity. * Diagnosis of manifest tetanus according to the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus), that is the presence of one or both of the following criteria with or without the history of specific wound or injury: * Sustained spasm of the facial muscles in which person appears grinning. * Painful muscular contractions
Exclusion criteria
* Age \< 18 years. * Absent criteria of manifest tetanus, as per the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus). * Incomplete medical record with missing data required to calculate the Tetanus Severity Score, Philips Score, or Dakar score. * Incomplete medical record with missing data regarding the primary outcome measure (survival to hospital discharge or in-hospital mortality).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Death from any cause. | From the date of onset of symptoms until the date of death or date of discharge from the hospital, whichever comes first, assessed up to 90 days. | Occurrence of death from any cause, assessed from the date of onset of symptoms up to 90 days. |
Countries
Egypt
Contacts
CONTACTSameh M Hakim, MD
STUDY_DIRECTORSameh M Hakim, MD
Ain Shams University Faculty of Medicine
Outcome results
None listed