Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients

Effect of Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07510022

Enrollment

400

Registered

2026-04-03

Start date

2023-06-01

Completion date

2025-06-01

Last updated

2026-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding Tendency, Cardiac Surgery, Egyptian Patients, Hot Climate

Brief summary

This work aimed to assess the effect of regional climatic differences on postoperative bleeding in Egyptian patients undergoing cardiac surgery with cardiopulmonary bypass, by comparing outcomes between patients from hot climate zones (Upper Egypt) and those from moderate climate zones (Lower Egypt).

Detailed description

Egypt experiences extremely high ambient temperatures, especially during the summer months, with daily highs frequently exceeding 40°C. Such climatic extremes can influence physiological homeostasis in surgical patients by altering fluid balance, cardiovascular strain, and hemostatic function. Seasonal and climatic variations have been linked to changes in cardiovascular surgical outcomes, including mortality, length of stay, and complication rates. Several large observational studies have noted increased bleeding or transfusion requirements in surgeries performed under certain environmental conditions, though findings remain inconsistent.

Interventions

PROCEDUREOpen heart surgery

Patients who underwent open heart surgery with cardiopulmonary bypass.

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥18 years. * Both sexes. * Egyptian nationality. * Underwent open-heart surgery with cardiopulmonary bypass. * Complete medical records and postoperative bleeding data are available.

Exclusion criteria

* Emergency surgeries * Pre-existing coagulopathy * Use of anticoagulants not discontinued prior to surgery * Re-do surgeries

Design outcomes

Primary

Measure	Time frame	Description
Incidence of mortality	24 hours postoperatively	Incidence of mortality was recorded.

Secondary

Measure	Time frame	Description
Incidence of morbidity	24 hours postoperatively	Incidence of morbidity was recorded.
Postoperative bleeding volume	24 hours postoperatively.	Total postoperative bleeding volume within the first 24 hours after surgery, measured by cumulative chest tube drainage.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 4, 2026