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A Functional Near- Infrared Spectroscopy Study on the Brain Activation Characteristics of Stroke Patients During Mirror Movement

A Functional Near- Infrared Spectroscopy Study on the Brain Activation Characteristics of Stroke Patients During Mirror Movement

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07509944
Enrollment
25
Registered
2026-04-03
Start date
2024-05-01
Completion date
2030-10-01
Last updated
2026-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, Upper Limb Function

Brief summary

After the selected patients are determined, the researchers of this study need to have full communication with the patients. The location is the rehabilitation ward of our hospital and the time is Before joining the group. During this process, the patient should be informed of the purpose, procedures and processes of the trial. The informed consent form should be signed by the patient himself/herself. Such as the patient Illiterate, the informed consent process was witnessed by an independent witness and signed. The subject pressed their fingerprint at the signature. In the study process fully Listen to and respond to the questions and opinions of the subjects or their representatives.

Interventions

DEVICEmirror image

Patients will be asked to place the affected hand in the mirror box. While quickly opening and closing the healthy hand, they should observe the reflection of the healthy hand in the mirror and imagine the affected hand doing the same movements.

BEHAVIORALhealthy hand movement

Patient will be asked to quickly open and grasp the healthy hand, and keep their eyes on the affected hand.

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* It meets the diagnostic criteria of the "Guidelines for the Prevention and Treatment of Cerebrovascular Diseases in China", and is diagnosed as cerebral infarction or cerebral hemorrhage by CT or MRI. * The first stroke occurred; * The muscle strength of the flexor and extensor muscles of the affected finger is ≤ grade 1. * Right-handed player * Muscle tone improvement: Asworth level 2 or below; * The disease course is within 6 months and the condition is stable. * Age: 18 to 75 years old, with normal vision and hearing or corrected to normal.

Exclusion criteria

* Those with an MMSE score less than 20, severe memory, communication and speech command comprehension disorders, and those who cannot cooperate with examinations and treatments; * Those with a history of epilepsy; * Those with a history of stroke, traumatic brain injury or brain tumor in the past; * Those with peripheral nervous system injuries other than stroke as diagnosed by imaging; * Those with visual spatial impairments such as visual field defects and unilateral neglect; * Skull defect or metal bone plates * For those who are not suitable for functional near-infrared examination; * Those with a history of intracranial surgery. * Patients with lesion areas in the cerebellum or brainstem.

Design outcomes

Primary

MeasureTime frame
fNIRS measured brain activationThe measurement of the primary outcome indicators occurred after the patients had received one week of hand function rehabilitation training.

Countries

China

Contacts

CONTACTJiasheng Zhu, Bachelor's
zhujiasheng321@sina.com+86 15157177433
CONTACTYifei Xia, master's
2523084@zju.edu.cn+86 19816890266

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 4, 2026