Pronostic Factors in Elderly Patients Admitted to the Intensive Care Unit for Aneurysmal Subarachnoid Hemorrhage

Pronostic Factors in Elderly Patients Admitted to the Intensive Care Unit for Aneurysmal Subarachnoid Hemorrhage Multicenter Retrospective Observational Study FAPPAR-HSA

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07508683

Acronym

FAPPAR-HSA

Enrollment

170

Registered

2026-04-02

Start date

2026-05-01

Completion date

2027-03-01

Last updated

2026-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid Hemorrhage, Aneurysmal

Keywords

Subarachnoid Hemorrhage, Elderly, Prognostic Factors, Intensive Care Unit

Brief summary

Subarachnoid hemorrhage (SAH) represents a significant proportion of hemorrhagic strokes. Severe SAH in elderly patients is associated with poorer outcomes compared to younger cohorts. Better characterization of both short- and long -term prognosis in these patients is necessary to facilitate medical decision-making in the intensive care unit (ICU) Primary Objective: The primary objective is to identify prognostic factors associated with poor functional outcome or death at 6 months (± 2 months) in elderly patients admitted to the ICU for SAH. Secondary Objectives: To evaluate in-hospital mortality among elderly patients admitted to the ICU for SAH. To describe the causes of in-hospital death (brain death, withholding/withdrawal of life-sustaining treatment \[WOLST\], other medico-surgical causes) in elderly patients admitted to the ICU for SAH. To describe the care trajectory following hospital discharge for elderly patients admitted to the ICU for SAH. To evaluate the mean length of stay in the ICU and in the hospital (acute care) for elderly patients admitted to the ICU for SAH. To identify prognostic factors associated with poor functional outcome or death at 1 year in elderly patients admitted to the ICU for SAH.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients hospitalized in ICU for aneurysmal subarachnoid hemorrhage * Aged 70 years or over the day of admission in ICU * Between Juin 30, 2021 and Juin 30, 2025

Exclusion criteria

* Decline to participate

Design outcomes

Primary

Measure	Time frame	Description
Modified Rankin Scale (MRS) et 6 months	6 months after ICU discharge	MRS : scale from 1(no symptoms) to 6 (dead) Good outcome : 0 - 2 Bad outcome: 3 - 6 The MRS grade is either collected if already available in the medical file or estimated retrospectively based on the patient neurological evaluation.

Secondary

Measure	Time frame	Description
Intrahospital mortality	Day 28	Intrahospital mortality = percentage of deaths occuring during the initial hospitalisation (in the ICU and the neurosurgical/neurological ward)
Cause of intrahospital death	Day 28	Percentage of the following categories: cerebral death, WOLST, surgical causes and medical causes
Destination upon hospital discharge	Day 28	Percentage of the following categories: Discharge to Home versus Rehabilitation Unit versus Another Inpatient Ward (non-neurosurgical)
Modified Rankin Scale upon discharge from hospital.	Day 28	MRS retrieved or estimated from patient's file data at the moment of ICU or neurosurgical ward discharge.

Countries

France

Contacts

CONTACTIonel M ALB, MD Intensive Care/Anesthesia

im.alb@chru-nancy.fr0033-661028367

STUDY_CHAIRViviane MARTIN, Chief of Research Departement

CHRU NANCY, DRCI

STUDY_CHAIRElodie JEANBERT, Methodologist, Statistician