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Comparison of the Eficacy of Mulligan Mobilization and Myofascial Release in Patients With Cervicogenic Headache

Comparison of the Eficacy of Mulligan Mobilization and Myofascial Release in Patients With Cervicogenic Headache

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07508410
Enrollment
90
Registered
2026-04-02
Start date
2025-12-01
Completion date
2026-12-01
Last updated
2026-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervicogenic Headache

Keywords

Neck pain, Massage therapy, Musculoskeletal diseases, Musculoskeletal manipulation, Rehabilitation, Complementary therapies

Brief summary

Cervicogenic headache (CBH) is defined as a headache caused by a disorder in the cervical spine, bones, discs, or soft tissue elements, which is also accompanied by neck pain. Unilateral, non-reversible oculo, fronto, temporal pain, pain that increases with poor neck positioning and incorrect neck movements, and may be seen with restricted movement in the upper cervical and occiput regions. The aim of this thesis is to compare the effectiveness of Mulligan mobilization technique and myofascial release methods used in the treatment of cervicogenic headache through a prospective clinical study.

Detailed description

This study is designed as a prospective, case-control, hospital-based study. Ninety patients aged 18-65 years who present to our hospital with cervicogenic headaches lasting at least 3 months will be included in the study. Participants will be given full information about the procedure and will provide written informed consent. The study will be conducted in accordance with the principles outlined in the Helsinki Declaration. All participants will undergo a comprehensive medical history and a detailed physical examination. Sociodemographic and clinical data, including age, gender, height, weight, education level, employment status, and income level, will be collected through standardized questionnaires. A total of 90 patients diagnosed with cervicogenic headache will be randomly assigned to three groups. Group 1 (n=30) will receive mulligan mobilization therapy three times a week for four weeks (12 sessions total) and a home exercise program. Group 2 (n=30) will receive myofascial release therapy three times a week for four weeks (12 sessions total), in addition to a home exercise program. Group 3 (n=30) will receive only a home exercise program three times a week for four weeks (12 sessions total). All patients will be evaluated at three different time points: before treatment, immediately after treatment is completed, and one month after treatment. The following assessments will be made during the evaluation process: To determine the frequency of cervicogenic headaches, patients were given a headache diary. Head and neck pain in the individuals included in the study was evaluated using the visual analog scale (VAS) before and after treatment. Participants' functional status was assessed using the headache impact test (HIT-6). The headache disability inventory/index (HDI) was used to measure the impact of headaches on daily life. The short form-12 (SF-12) questionnaire was used to assess the patients' quality of life.

Interventions

Each patient was asked to sit comfortably, and the therapist performing the treatment stood beside them. The patient's head was free and positioned between the therapist's right forearm and body, with the therapist standing to the patient's right. The therapist then placed their right index, middle, and ring fingers on the base of the occiput and held their right little finger on the spinous process of C2. Next, gentle pressure was applied ventrally and upward (45 degrees) to the lateral edge of the left thenar process and the right little finger. The gliding motion was applied rhythmically (three times per second) ten times. The therapist continuously slid the joint and actively asked the patient to move their head towards the side where the dysfunction and pain were located. He held the SNAG technique for 10 seconds. This technique was repeated 10 times over approximately 8 minutes.

The procedure was performed on the upper part of the trapezius muscle and the levator scapulae muscle. The patient was in a seated position, hips higher than knees, feet slightly in front of the knees and in full contact with the ground. The therapist stood behind the patient. Myofascial release of the trapezius was performed unilaterally with a soft fist, while the patient lowered their head forward and slowly rotated, creating a tension line from the middle of the trapezius towards the acromion process. During this time, the patient was asked to turn their head to the opposite side. Then, the therapist applied resistance to the opposite side of the rotation for 10 seconds. MGT was repeated 5 times on the trapezius. The therapist applied the same unilateral contraction, but the tension line was slightly laterally towards the lower edge of the scapula. The therapist then asked the patient to tilt their head forward to increase resistance on the levator scapula for 10 seconds.

OTHERExercise therapy

All patients were given a home exercise program consisting of neck joint range of motion exercises, trapezius stretches, and isometric strengthening exercises for the neck muscles. The home exercise program was initiated with 3 sets of 10 repetitions per day. The exercises were demonstrated practically by the physician, and all patients were given a printed sheet showing how to perform the exercises. Patients were contacted by phone once a week to inquire about their adherence to the exercise program and were encouraged to follow it. Patients with exercise adherence below 75-80% were excluded from the study.

Sponsors

Konya Beyhekim Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Individuals aged 18-65 * Having experienced neck or headache for 3 months * Meeting the diagnostic criteria for cervicogenic headache; * Unilateral pain * Reduced range of motion in the neck * Ipsilateral shoulder discomfort * Ipsilateral arm discomfort * Pain that worsens with different neck movements and is painful on palpation

Exclusion criteria

* Migraine * Cluster headache * Cervical radiculopathy * Entrapment neuropathy * Myelopathy * Rheumatoid arthritis * Undergoing cervical spinal surgery * Pregnant women * Those who received physical therapy within 6 months * Those with a history of major psychiatric illness * Those with a history of uncontrolled systemic diseases (cardiovascular, pulmonary, hepatic, renal, hematological) * Those with a history of uncontrolled systemic endocrine diseases (dm, hyperthyroidism)

Design outcomes

Primary

MeasureTime frameDescription
Frequency of cervicogenic headacheBeginning, week 4, and week 8To determine the frequency of cervicogenic headaches, patients were given a headache diary.
assessment of pain intensity VAS pain (0-10)Beginning, week 4, and week 80 no pain, 10 unbearable/maximum pain

Secondary

MeasureTime frameDescription
Headache impact scale (HIT)Beginning, week 4, and week 8This scale was used to assess how much headaches affected patients' school, home, and social lives. The score range is 36-78. Higher scores indicate that headaches have a greater impact on your life.
Headache disability inventory/indexi ( HDI )Beginning, week 4, and week 8This 25-item questionnaire helps assess the impact of headaches and their treatment on daily life. Patients answer the questions on the questionnaire with yes (4 points), sometimes (2 points), and no (0 points). The total score is calculated out of 0-100. The results are classified as follows: 0-14 points no/very mild disability, 15-36 points mild, 37-60 points moderate, and 61-100 points severe disability.
Assessment of quality of life short form-12Beginning, week 4, and week 8It consists of 12 questions, and the answers to these questions are used to calculate a series of subscales and an overall general health score. Subscale scores are graded on a scale of 0 to 100. As the score increases from 0 (zero) to 100 (one hundred), it means the health condition is improving.

Countries

Turkey (Türkiye)

Contacts

CONTACTBURCU VURAL
burcuvural97@gmail.com+905389507278

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 3, 2026