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Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone

Comparison of Mean Duration of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving US Transversus Abdominis Plane Block (TAP) With Bupivacaine and Dexmetomidine vs Bupivacaine nd Dexmethasone

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07508202
Enrollment
60
Registered
2026-04-02
Start date
2026-03-27
Completion date
2026-06-26
Last updated
2026-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dexmedetomidine, Post Operative Analgesia, TAP Block

Keywords

Post opertive analgesia in lower abdominal surgeries

Brief summary

Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding drugs to local anesthetic regimen

Detailed description

TAPP block can provide significant post operative analgesia following lower abdominal surgery and its duration can be prolonged by adding adjuvants to local anesthetics.

Interventions

DRUGDexmedetomidine

20 ml 0.25% Bupivacaine along with 0.5 Mcg/kg of Dexmedetomidine will be given in TAPP block bilaterally

DRUGDexamethasone

20 ml 0.25% Bupivacaine along with 4 mg of Dexamethasone will be given in TAPP block bilaterally

Sponsors

Pakistan Institute of Medical Sciences
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* ASA I and ASA II BMI 25-35 kg/m2 Lower abdominal surgeries below L2-L3 leves

Exclusion criteria

* Infection at block site Coagulopathy Antiplatelet

Design outcomes

Primary

MeasureTime frame
Resuce analgesiaTime in the post operative period when patient first demands rescues analgesia will be noted in minutes

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 15, 2026