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Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders

Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders: Evidence From Lateral Ankle Sprain and Patellofemoral Pain Syndrome

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07508163
Acronym
LAS-PFPS
Enrollment
90
Registered
2026-04-02
Start date
2026-03-30
Completion date
2026-04-27
Last updated
2026-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankle Sprains, Patellofemoral Pain Syndrome

Keywords

Postural stability, APSI, MLSI, OASI, LAS, PFPS

Brief summary

Lateral ankle sprain (LAS) and patellofemoral pain syndrome (PFPS) are common musculoskeletal conditions associated with postural instability. However, the direction-specific nature of balance deficits and comparative patterns across these conditions remain unclear. Therefore, the aim of this study is to compare overall, mediolateral, and anteroposterior postural stability indices among individuals with LAS, PFPS, and healthy controls using the Biodex Balance System

Interventions

DIAGNOSTIC_TESTdiagnosis of APSI, MLSI, OASI

To compare overall, antero-posterior and mediolateral postural stability indices among individuals with lateral ankle sprain, patellofemoral pain syndrome, and healthy controls using the Biodex Balance System.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

Inclusion criteria for the lateral ankle sprain group will include participants with a clinically confirmed history of unilateral lateral ankle sprain, who are at least three months post-injury to avoid acute inflammatory effects, and who report residual symptoms such as pain or functional limitation. Participants in the patellofemoral pain syndrome group will have a clinical diagnosis of patellofemoral pain syndrome characterized by anterior or retropatellar knee pain aggravated by functional activities such as stair climbing, squatting, or prolonged sitting, with symptoms persisting for at least three months. Healthy control participants will have no history of lower limb musculoskeletal injury, pain, or functional impairment within the past three months and will be matched to the patient groups based on age and sex. All participants across groups will be able to stand independently without assistive devices and will demonstrate sufficient cognitive ability to understand and follow study instructions

Design outcomes

Primary

MeasureTime frameDescription
APSIone shot assessment within one weekanterior-posterior stability index
MLSIone shot assessment within one weekMedial-lateral stability index
OASIone shot assessment within one weekoverall stability index

Contacts

CONTACTAzza M Abdelmohsen, professor
dr_azzamohammed@yahoo.com01145046304
PRINCIPAL_INVESTIGATORAzza Abdelmohsen, professor

Cairo University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 10, 2026