End Stage Cronic Kidney Disease, Hemodialysis
Conditions
Keywords
Intradialytic Exercise, Hemodialysis, End Stage Cronic Kidney Disease
Brief summary
Objective: To evaluate the effects of a six-month intradialytic aerobic exercise program on left ventricular ejection fraction in patients with end-stage kidney disease undergoing maintenance hemodialysis. Materials and Methods Design: Open-label, single-center, quasi-experimental, single-group study with pre- and post-intervention measurements. Study setting: the outpatient hemodialysis unit of the National Institute of Medical Sciences and Nutrition Salvador Zubirán. Participants: Patients aged ≥18 years with chronic kidney disease on hemodialysis for at least three months, who are at their dry weight. Procedures: An echocardiogram will be performed post-hemodialysis. Subsequently, patients will undergo a 30-minute intradialytic aerobic exercise program at submaximal intensity during the second hour of dialysis, three times per week for six months. At the end of the six-month period, a post-hemodialysis echocardiogram will be repeated.
Interventions
OTHERIntradialytic aerobic exercise program
A six-month intradialytic aerobic exercise program consisting of 30-minute sessions at submaximal intensity, performed during the second hour of hemodialysis three times per week.
Sponsors
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults aged ≥18 years * Receiving hemodialysis with a stable prescription for at least 3 months * At their prescribed dry weight * Provision of written informed consent
Exclusion criteria
* Active cardiovascular disease within the past 3 months * Left ventricular ejection fraction \<40% * Physical and/or cognitive impairment precluding exercise * Blood pressure \>160/110 mmHg
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Left ventricular ejection fraction | From study enrollment to the initiation of the exercise program (within a maximum of 6 weeks), and subsequently from completion of the exercise program to up to 6 weeks thereafter | Left ventricular ejection fraction measured by transthoracic echocardiogram |
Countries
Mexico
Outcome results
None listed