Sepsis
Conditions
Brief summary
Fluid responsiveness refers to the ability of the left ventricle to significantly increase stroke volume following fluid administration, and its assessment is critical in managing acute circulatory failure while avoiding fluid overload.Infraclavicular axillary vein collapsibility index is a substitute for inferior vena cava collapsibility index in assessment for the need of fluid resuscitation in spontaneously breathing sepsis related acute circulatory failure patients.
Interventions
OTHERInfraclavicular axillary vein collapsibility index
Assessment of the infraclavicular axillary vein collapsibility index to predict fluid responsiveness in spontaneously breathing patients in sepsis related acute circulatory failure.
Sponsors
Ain Shams University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients ≥18 years. * Patients with sepsis must meet at least two or more criteria of systemic inflammatory response syndrome (SIRS). * Spontaneously breathing patients. * Clinical signs of acute circulatory failure.
Exclusion criteria
* Patients below the age of 18 years. * Mechanically ventilated patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The infraclavicular axillary vein collapsibility index changes in response to fluid challenge. | Fluid challenge over 10 min time period. | The infraclavicular axillary vein collapsibility index changes in response to fluid challenge. A collapsibility index greater than fifty percent in spontaneously breathing patients is commonly associated with a right atrial pressure between zero and five millimeters of mercury. |
Countries
Egypt
Contacts
CONTACTIbrahim Mamdouh Esmat
Outcome results
None listed