Gynecologic Surgery, Postoperative Recovery, Anesthesia
Conditions
Brief summary
This study aims to compare the effects of combined intravenous-inhalational anesthesia versus inhalational anesthesia alone on postoperative recovery in patients undergoing elective gynecologic surgery. A total of 100 patients, aged 18-65 years and classified as ASA I-III, scheduled for elective gynecologic procedures at Sakarya University Faculty of Medicine Training and Research Hospital, will be included. The sample size was calculated based on the primary outcome, the Quality of Recovery-15 (QoR-15) score. Patients will complete the QoR-15 questionnaire preoperatively, before knowing which anesthesia method will be applied. Postoperative QoR-15 scores will be collected on postoperative days 1 and 2, and intraoperative data will be obtained from anesthesia records. The study evaluates postoperative recovery using QoR-15 scores, covering physical comfort, emotional state, psychological support, pain, and ability to perform daily activities. Higher scores indicate better recovery, whereas lower scores indicate impaired postoperative recovery.
Interventions
Patients will receive a combination of intravenous anesthetic agents and inhalational anesthetic gases during elective gynecologic surgery. The specific anesthetic drugs and doses will follow routine clinical practice. Postoperative recovery will be assessed using the Quality of Recovery-15 (QoR-15) questionnaire on postoperative days 1 and 2.
DRUGInhalational Anesthesia Only
Patients will receive only inhalational anesthetic gases during elective gynecologic surgery, following routine clinical practice. Postoperative recovery will be assessed using the QoR-15 questionnaire on postoperative days 1 and 2.
Sponsors
Sakarya University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
Patients will be randomly assigned in a parallel design to one of two groups: Combined intravenous-inhalational anesthesia group Inhalational anesthesia only group Each patient will receive only one anesthesia method during their elective gynecologic surgery. Outcomes will be assessed using the Quality of Recovery-15 (QoR-15) questionnaire on postoperative days 1 and 2. This design allows a direct comparison of postoperative recovery between the two anesthesia methods.
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Patients aged 18-65 years 2. Scheduled for elective gynecologic surgery at Sakarya University Faculty of Medicine Training and Research Hospital 3. Classified as ASA I-III 4. Able to understand and complete the QoR-15 questionnaire 5. Provided written informed consent
Exclusion criteria
1. Severe comorbidities (beyond ASA III) 2. Patients with advanced neurological disease or cognitive impairment 3. Known allergy to anesthetic drugs used in the study 4. Classified as ASA IV-V 5. Refusal to participate in the study 6. Emergency or urgent surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative recovery using QoR-15 | Postoperative Day 1 and Postoperative Day 2 | Postoperative recovery will be assessed using the Quality of Recovery-15 (QoR-15) questionnaire, a validated patient-reported outcome measure. The questionnaire evaluates physical comfort, emotional state, psychological support, pain, and ability to perform daily activities. Higher scores indicate better recovery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain score | Postoperative hours 6, 12, and 24 | Pain will be assessed using a standard numerical rating scale (0-10) at postoperative hours 6, 12, and 24. Higher scores indicate more pain. |
| Postoperative nausea and vomiting (PONV) incidence | Postoperative hours 0-24 | Incidence of nausea and vomiting will be recorded in the first 24 hours after surgery. |
| Length of stay in post-anesthesia care unit (PACU) | Postoperative period (PACU stay), assessed up to 10 days | Duration of stay in PACU will be recorded in minutes from admission to discharge. |
Countries
Turkey (Türkiye)
Contacts
CONTACTmelike kar ünlü, MD
Outcome results
None listed