Shear Wave Elastography for Predicting Extracorporeal Shock Wave Lithotripsy Outcomes in Pediatric Renal Stones

Evaluating Shear Wave Elastography as a Predictor of Extracorporeal Shock Wave Lithotripsy Outcomes and Stone Composition in Children "A Prospective Study"

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07506031

Acronym

SWE-ESWL

Enrollment

110

Registered

2026-04-01

Start date

2025-12-02

Completion date

2026-06-01

Last updated

2026-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Urolithiasis

Brief summary

This prospective study aims to evaluate the role of shear wave elastography (SWE) as a non-invasive and radiation-free tool for predicting the success of extracorporeal shock wave lithotripsy (ESWL) in pediatric patients with renal stones. Currently, computed tomography (CT)-derived Hounsfield units (HU) are used to estimate stone hardness; however, repeated radiation exposure is a concern in children. SWE may provide an alternative method by assessing stone stiffness using ultrasound. Pediatric patients under 18 years with renal stones (6-20 mm) scheduled for ESWL will be included. SWE measurements will be performed prior to treatment, and patients will be followed for 3 months to assess treatment outcomes. The primary outcome is ESWL success, while secondary outcomes include correlation between SWE and HU, number of ESWL sessions required, prediction of stone composition, and assessment of the relationship between SWE measurements and stone composition. This study seeks to determine whether SWE can serve as a reliable predictor of ESWL outcomes, correlate with stone composition, and reduce the need for radiation-based imaging in children.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Years to 18 Years

Healthy volunteers

Inclusion criteria

* Inclusion criteria: 1. Single Renal stones measured 6- 20 mm in maximal dimension. 2. ESWL will be planned as the first line of treatment.

Exclusion criteria

1. Patients with internal ureteral stent. 2. ureteral stones. 3. abnormal renal anatomies (pelvic kidney, horseshoe kidney, and rotational anomaly). 4. active UTI at time of ESWL. 5. coagulopathy .

Design outcomes

Primary

Measure	Time frame	Description
ESWL Success Rate	3 months with maximum 3 sessions ESWL	Treatment success defined as absence of stone fragments or presence of clinically insignificant residual fragments ≤2 mm on imaging, without symptoms, obstruction, or urinary tract infection.

Secondary

Measure	Time frame	Description
Secondary Outcomes Related to SWE and ESWL	Up to 3 months after ESWL	Assessment of secondary outcomes including: 1. correlation between shear wave elastography (SWE) values and CT-derived Hounsfield units (HU). 2. Correlation between SWE and stone composition.

Countries

Egypt

Outcome results