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Influence of Training Session Duration on Improvements in Physiological Resilience to Exercise

Influence of Training Session Duration on Improvements in Physiological Resilience to Exercise

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07504003
Acronym
RED
Enrollment
40
Registered
2026-03-31
Start date
2026-04-08
Completion date
2029-02-28
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endurance Exercise, Healthy Volunteers

Keywords

physiological resilience, endurance exercise, training session

Brief summary

During prolonged endurance exercise, certain physiological variables deteriorate depending on the duration of the exercise. Physiological resilience has therefore been defined as the ability to resist these changes and appears to be an important performance factor in endurance sports. For example, most studies in this field have investigated changes in cycling power output associated with the first ventilatory threshold (VT1), a marker of an individual's endurance capacity, after prolonged endurance exercise. To date, only two studies have examined the effects of training on resilience. The first compared the effectiveness of two training programs, one with low-intensity sessions and the other with high-intensity sessions, with no difference between the conditions. The second study showed that incorporating strength training into a running training program was more effective at improving resilience than running alone. However, the influence of training session duration on resilience remains unknown. Only one observational study has shown that in a group of runners of similar ability, those who were used to doing long sessions had better resilience than those who only did short sessions.

Detailed description

We hypothesize that at equal intensity and volume, a less frequent training consisting of long sessions would be more effective in improving physiological resilience than a more frequent training composed of short sessions.

Interventions

OTHERLong sessions

Training frequency of 2 long sessions per week

OTHERShort sessions

Training frequency of 5 short sessions per week

Sponsors

Centre Hospitalier Universitaire de Saint Etienne
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Subjects who engage in rigorous cardiovascular activity (e.g., endurance sports, team sports, combat sports, etc.) for a maximum of two hours per week * Ability to understand, speak, read, and write French * Affiliated with or beneficiaries of a social security system * Having freely given their written consent after being informed of the purpose, procedure, and potential risks involved

Exclusion criteria

* Subjects with chronic joint conditions (e.g., recurrent sprains, patellar or ligament problems). * Subjects with one or more heart conditions, including ischemic, valvular, arrhythmic, hypertensive, congenital, or hypertrophic heart disease. * Participants under guardianship or conservatorship. * Subjects with chronic or central neurological conditions. * Subjects who report having taken products prohibited by the World Anti-Doping Agency. * Pregnant or breastfeeding women. * Subjects who are unable to understand the purpose and conditions of the study and unable to give their consent. * Persons deprived of their liberty by judicial or administrative decision, persons receiving psychiatric care under Articles L. 3212-1 and L. 3213-1 who are not covered by the provisions of Article L. 1121-8, and persons admitted to a health or social care facility for purposes other than research.

Design outcomes

Primary

MeasureTime frameDescription
Power (watt) output at ventilatory threshold 1 (VT1)At inclusion, Day 80.the power (Watt) output at the VT1 measured by the difference of the power output (% decrease after 4 hours of cycling) between measurements taken before and after a training program. The results will be compared between group benefiting from long sessions and group from short sessions

Secondary

MeasureTime frameDescription
a) Degree of change in heart rate (beats per minute),Day 7, Day 85Degree of changes in heart rate (beats per minute) during a 4-hour endurance cycling session, as measured by a heart rate monitor. The results will be compared between group benefiting from long sessions and group from short sessions
Rate of change in oxygen consumption (in L of O₂/min)Day 7, Day 85the rate of change in oxygen consumption (in L O₂/min) during a prolonged 4-hour endurance cycling exercise, quantified by measuring gas exchange (calculated using the equations of Jeukendrup and Wallis). The results will be compared between group benefiting from long sessions and group from short sessions
b) The Power (watt) output at ventilatory threshold 2 (VT2)At inclusion, Day 80.the power (Watt) output at the VT2 measured by the difference of the power output (% decrease after 4 hours of cycling) between measurements taken before and after a training program. The results will be compared between group benefiting from long sessions and group from short sessions

Countries

France

Contacts

CONTACTLéonard FEASSON, PHD
leonard.feasson@chu-st-etienne.fr(0)477120383
PRINCIPAL_INVESTIGATORLéonard FEASSON, PHD

CHU de Saint-Etienne

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 15, 2026