Cataract, Intraocular Lens
Conditions
Keywords
biometry, keratometry, axial lenght, intraocular lens, cataract
Brief summary
This study aim to evaluate the agreement of ocular biometric parameters and intraocular lens between two devices (OA-2000 and Pentacam AXL) in patients with cataract. Participants will be measured ocular biometric parameters once with each device in a random order by the same experienced operator.
Detailed description
This study was conducted as a prospective cross-sectional study to evaluate Agreement of ocular biometry and intraocular lens power between swept-source optical coherence tomography with Placido-disc topography (OA-2000) and Scheimpflug tomography with partial coherence interferometry (Pentacam AXL) in cataract patients The study performed at the Ophthalmology Outpatient Department, Burapha University Hospital, Chonburi, Thailand. The study protocol adhered to the tenets of the Declaration of Helsinki and received formal approval from the Institutional Review Board, Burapha University. Prior to the commencement of any measurements, all participants acknowledged comprehensive study information and provided written informed consent. A total of 94 participants, aged 18 years or older, diagnosed with cataracts and scheduled for cataract surgery, were enrolled. Exclusion criteria included history of corneal trauma, prior ocular surgery, the use of contact lenses within two weeks of measurement, and the presence of other concurrent ocular pathologies. For each participant, right eye was preferentially selected for analysis; left eye was only utilized if right eye met any of the predefined exclusion criteria. Measurement protocol Both devices, OA-2000 and Pentacam AXL Wave were calibrated daily before clinical use to ensure technical accuracy. All measurements were performed by one experienced examiner to eliminate inter-observer variability. Participants were instructed on proper head positioning and fixation, with a complete blink prior to each automated image capture. Measurements were obtained once for each device, with the sequence of instrumentation determined in a random order. The study evaluated several ocular biometric parameters: flat keratometry (K1), steep keratometry (K2), mean keratometry (Km), corneal astigmatism, vector analysis (J0 and J45), ACD, WTW, and AL. For the calculation of IOL power, The Acrysof SN60WF model (Alcon Laboratories, Fort Worth, Texas, USA) was used as the reference, utilizing the keratometric index of 1.3375. IOL power calculations were performed using three distinct formulas: SRK/T, Barrett Universal II, and Hoffer Q.
Interventions
Measurement technology using swept-source optical coherence tomography with Placido-disc topography
Measurement technology using Scheimpflug tomography with partial coherence interferometry
Sponsors
Study design
Eligibility
Inclusion criteria
* Participants aged 18 years or older, diagnosed with cataracts and scheduled for cataract surgery
Exclusion criteria
* History of corneal trauma * Prior ocular surgery * The use of contact lenses within two weeks of measurement * The presence of other concurrent ocular pathologies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Agreement of Intraocual lens power between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | Intraocular lens power calculated using SRK/T, Barrett Universal II, and Hoffer Q formulas in diopters |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Agreement of flat keratometery(K1) between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | flat keratometery(K1) in diopters |
| Agreement of steep keratometry(K2) between OA-2000 and Pentacam AXL in cataract patient | Immediately after participating in the study | steep keratometry(K2) in diopters |
| Agreement of mean keratometry(Km) between OA-2000 and Pentacam AXL in cataract patient | Immediately after participating in the study | Mean keratometry(Km) in diopters |
| Agreement of anterior chamber depth (ACD) between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | Anterior chamber depth (ACD) in millimeters |
| Agreement of white-to-white distance (WTW) between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | White-to-white distance (WTW) in millimeters |
| Agreement of axial lenght (AL) between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | Axial lenght (AL) in millimeters |
| Agreement of corneal astigmatism between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | corneal astigmatism in diopters |
| Agreement of J0 between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | J0 is vector analysis of corneal astigmatism; measures astigmatism at 90° and 180° |
| Agreement of J45 between OA-2000 and Pentacam AXL in cataract patients | Immediately after participating in the study | J45 is vector analysis of corneal astigmatism; measures astigmatism at 45° and 135° |
Countries
Thailand
Contacts
Burapha University